Epimysium
Envelopes the muscle (epi = upon, my = muscle).
Dense irregular connective tissue.
Perimysium
Divides the muscle into multiple wedges (peri = around); it covers each fascicle.
Each fascicle comprises skeletal muscle cells (aka skeletal myocytes or muscle fibers).
Endomysium
Surrounds the muscle cells.
Loose areolar connective tissue that maintains the extracellular environment for proper muscle cell functioning.
MUSCLE FASCICLE
Muscle cells
They are multinucleated (meaning, each cell contains many nuclei).
Each skeletal myoctye comprises numerous myofibrils.
This reality reflects the actual process of muscle cell formation. Mature muscle cells form from fused myoblast cells (embryonic cells) and each myoblast contributes its nucleus to the adult muscle cell.
