#hnmt

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Deficiency of Enzyme Histamine N-Methyltransferase (HNMT) Linked to Nervous System And Brain Disorders - Drugs, Choline Deficiency Inhibit HNMT Enzyme

AGGRESSION AND IRRITABILITY ARE TWO EARLY SIGNS OF AN ALLERGIC REACTION, POTENTIAL HISTAMINE TOXICITY Aggression/irritability are early signs of allergic reaction."Histamine N-methyltransferase regulates aggression and the sleep-wake cycle"https://t.co/BXGkIHu0imHistamine N-methyltransferase regulates aggression and the sleep-wake cycle. 7. 10.1038/s41598-017-16019-8. https://t.co/bFhyfLnR8C—…

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more on HNMT dysfunction bc. uhhh that's where the dysautonomia is from holy shit:

For instance, the main symptoms of histamine intolerance within the nervous system are anxiety, dizziness, fatigue, insomnia, myoclonic twitching and unrest.[10] Overall, the symptoms of flawed HNMT activity are typical of symptoms of histamine intolerance, including allergic rhinitis, urticaria (hives), and peptic ulcer disease.[7]

wikipedia

[cfsfmmcsandrelatedstudies]

Notes on Histamine Intolerance

(To discuss with your doctor) 1) Prick tests and RAST tests aren't used to diagnose histamine intolerance. 2) Histamine tests are available. 3) DAO tests are available in Canada & Europe. Keep in mind DAO deficiency is more closely associated with GI symptoms where HNMT deficiency is more closely associated with respiratory symptoms 4) If your doctor recommends vitamin B6, please read labels for the RDA since too much vitamin B6 can cause nerve damage.