can't complain about a guy "mansplaining" to you because what if he is autistic and excited to share his special interest. can't call a guy getting into your laundry a pervert because what if he has gender dysphoria. can't say "all men" because this other guy is actually into painting his nails and also not afraid to cry so clearly not all men. hey guys when you say something is for the girls and the gays can you include me in that as well. can you. can you?
meanwhile all opinionated women are bitchy Karens, all lesbians with boundaries are fascist TERFs, and all GNC women are trans eggs. but sure, modern feminism is the most progressive it's ever been!
Tim Friede’s blood is now the source of a potential new universal anti-venom, following hundreds of meticulous bites and venomous injections
"Tim Friede’s YouTube channel is home to a collection of videos depicting the Wisconsin-native truck mechanic subjecting himself to purposeful snake bites, blood slowly dripping down his arms.
For the past 20 years, Friede has been one of the most notorious “unconventional” medical researchers, undergoing over 200 bites from the world’s deadliest snakes — and more than four times as many — 850 — venomous injections.
He did it all in the name of science.
According to the World Health Organization, an estimated 100,000 people are killed by snake bites each year, with countless more being disabled by the venom of the deadly reptiles.
While life-saving anti-venom is available, very few countries actually have the capacity to produce it properly, given that most bites occur in remote and rural areas, and anti-venom requires arduous sourcing and accuracy.
But Friede’s blood is now full of antibodies, following decades of strategic exposure to the neurotoxins of mambas, cobras, and other lethal slithering critters.
His blood is now the source material researchers are using to develop an anti-venom capable of neutralizing a broad spectrum of snake bites...
Friede started this hobby — which he is indeed adamant no one else tries at home — out of sheer curiosity in childhood. After playing with harmless garter snakes in his youth, he began keeping more dangerous species of snakes as pets. At one point, he had 60 of them in his home basement.
In 1999, he began extracting venom from his snakes, drying it, diluting it, and injecting himself with tiny doses — keeping meticulous records as he went.
He had one major hospitalization in 2001, when he was paralyzed and in a coma for four days. But instead of giving up, he doubled down.
“In hindsight, I’m glad it happened,” Friede told The Times. “I never made another mistake.”
Jacob Glanville, an immunologist and founder of biotech company Centivax, stumbled on Friede’s videos.
Now, Friede is the director of herpetology at Centivax and serves as something of a “human lab” to Glanville.
“For a period of nearly 18 years, [Tim] had undertaken hundreds of bites and self-immunizations with escalating doses from 16 species of very lethal snakes that would normally a kill a horse,” Glanville told The Guardian.
“It blew my mind. I contacted him because I thought if anyone in the world has these properly neutralizing antibodies, it’s him.”
To develop the new anti-venom, Glanville and his fellow researchers identified 19 of the world’s deadliest snakes — in the elapid family — which kill their prey by injecting neurotoxins into their bloodstream, paralyzing muscles (including the big, important ones, like the heart and lungs).
The trouble is, each species in the elapid family has a slightly different toxin, meaning they would each require their own anti-venom.
But Friede’s blood contains certain fragments of each of these toxins; protein molecules seen across the various species. Because of his decades of service to science, his blood also contains the antibodies required to neutralize these toxins, preventing them from sticking to human cells and causing harm.
Combining the antibodies LNX-D09, SNX-B03, and a small molecule called varespladib that inhibits venom toxins, Centivax has successfully created a treatment effective against the entire range of 19 species’ toxins.
Their work, which was recently published in the journal Cell, will soon be tested outside of the lab.
Trials will start with using the serum to treat dogs admitted to Australian veterinary clinics for snake bites. Assuming that goes well, the next step will be to administer human tests.
Researchers also believe that because the serum stems from a human, this should also lower the risk of allergic reactions when being administered to other people.
“The final product would be a single, pan-anti-venom cocktail,” Professor Peter Kwong of Columbia University, a senior author of the study, told The Times.
Or, he added, they could make two: “One that is for the elapids, and another that is for the viperids, because some areas of the world only have one or the other.”
As for Friede, he maintains his affinity for snakes, though his last bite was in November 2018, when he said “enough is enough,” according to The New York Times.
By then, he had certainly done enough. His pursuit of immunity could feasibly save countless lives.
“I’m really proud that I can do something in life for humanity,” Friede told The New York Times, “to make a difference for people that are 8,000 miles away, that I’m never going to meet, never going to talk to, never going to see, probably.”
robert eggers freaks me the fuck out. near all of his movies have at least one scene of a super baby faced technically legal actress portraying a canonically underaged (like, below 16 too) girl get naked and/or engage in sexual acts. why is that guy obsessed with having naked young women and girls in his films.
Brazil has one of the highest femicide rates globally, serious issues with wealth inequality and secure housing, violence against indigenous peoples and their tribes, and sex trafficking, but sure, imprisoning a woman for correctly pointing out that it's possible to sex skeletons is where their resources should be going. 🙄
and even if it wasnt a fact???? imagine if a flat earther could go to jail for what theyre saying?? imagine if everyone who makes "adam and eve not adam and steve" jokes could go to jail?????
this is like the end of free speech for women in brazil if she gets imprisoned.
There's a lot sickening about the human rights violations occurring against Adriana Smith right now, but one of the ones that's really searing me is that they're gonna use her death and experimentation as a medical lesson or method of "saving babies" that they'll try not to bring up in textbooks. It's been that same pattern for the entirety of gynecology in America; Black women are used as guinea pigs to test shit in order to become "good enough" to save everyone else. Not bad enough that were 3x more likely to die in childbirth when we walk into the birthing room, not bad enough that no one takes our pain seriously at any medical stage. No, NOW I gotta worry about my family having to pay the bills to keep my dead body warm for a Black baby that, if it's born, will face a world that will treat it just as inhumanely as the Black mother it came from. Bc they're not gonna give a shit about it once it's born. CRAZY.
This journey has been deeply saddening and heartbreaking since F… April Newkirk needs your support for Help Adriana's Family During This Hea
Anyway read Medical Apartheid by Harriet A Washington, if you need "receipts" for how Black bodies have long been abused for the "sake of medical progress".
All the Black children left to die or were outright murdered by the state, but NOW we wanna "save the baby". All the Black dead was somebody's baby too, Adriana was somebody's baby, or does it only matter when it's time to control someone's body? Even in DEATH we can't escape indignities. Ghoulish fucking country.
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