5-Nitroindoline-2,3-dione (CAS No. 611-09-6) in Tucatinib Intermediates | VidgasTech
Introduction
The global pharmaceutical industry heavily relies on high-purity intermediates for the synthesis of complex drug molecules. One such important intermediate is 5-Nitroindoline-2,3-dione (CAS No. 611-09-6), a compound widely used in the preparation of Tucatinib Intermediates. Tucatinib is a potent and selective HER2 inhibitor used in targeted cancer therapies, particularly for the treatment of HER2-positive breast cancer.
At VidgasTech, we specialize in the manufacturing and supply of fine chemicals and pharmaceutical intermediates like 5-Nitroindoline-2,3-dione, supporting R&D and production needs across the pharmaceutical sector.
Chemical Information
Chemical Name: 5-Nitroindoline-2,3-dione
CAS Number: 611-09-6
Molecular Formula: C8H4N2O4
Molecular Weight: 192.13 g/mol
Appearance: Yellow crystalline powder
Purity: ≥98% (customizable as per client requirement)
Role in Tucatinib Intermediate Synthesis
5-Nitroindoline-2,3-dione is a key starting material or intermediate used in the multi-step synthesis of Tucatinib Intermediates. It provides the indoline framework essential for forming the HER2 inhibitor’s core structure. During the synthesis process, it undergoes selective reduction, condensation, and functional group transformations that contribute to building the active Tucatinib molecule.
High-purity intermediates like this compound ensure efficient reaction yields, superior product quality, and reproducibility in pharmaceutical manufacturing.
Applications
Intermediate in HER2 inhibitor (Tucatinib) synthesis
Pharmaceutical R&D and drug discovery
Organic synthesis of heterocyclic compounds
Fine chemical and specialty compound manufacturing
Why Choose VidgasTech
VidgasTech is a trusted name in the global chemical and pharmaceutical industry, offering a wide range of intermediates and fine chemicals. Our focus is on delivering high-quality, reliable, and cost-effective chemical solutions.
Our Key Advantages:
High-purity products with complete analytical data (COA, MSDS, TDS)
Custom synthesis and contract manufacturing options
Global logistics and timely delivery
Expert R&D and technical support
Compliance with industry standards and regulations
With a customer-centric approach and advanced infrastructure, VidgasTech ensures that every product meets international quality benchmarks.
Packaging & Supply
Available in 1 kg to 25 kg HDPE containers or custom packaging
Safe and secure export-grade packing
Worldwide shipping with complete documentation support
Conclusion
5-Nitroindoline-2,3-dione (611-09-6) plays an essential role in the synthesis of Tucatinib Intermediates, a key step toward the production of advanced anti-cancer drugs. The demand for such high-quality intermediates continues to grow with the increasing focus on targeted cancer therapies.
By choosing VidgasTech, you partner with a reliable manufacturer and supplier committed to innovation, quality, and scientific excellence.
About VidgasTech
VidgasTech is a leading manufacturer and exporter of pharmaceutical intermediates, fine chemicals, and specialty compounds, serving industries across the globe. With a dedication to quality and customer satisfaction, VidgasTech supports research, production, and innovation in modern pharmaceuticals.
🌐 Website: www.vidgastech.com
