#hepatic

[drhoz]

#2217 - Marchantia sp. - Liverwort

Growing in delightful abundance next to the Visitors Centre at the Craters of the Moon. Probably the Common Liverwort Marchantia polymorpha, which is found in damp and sometimes submerged habitats everywhere except Antarctica. Hardy enough to be a horticultural weed, and potentially a problem in caves with artificial light, and frequently the first plant to occupy burned areas.

Dioicous, having separate male and female plants. The umbrella-shaped ones in the top photo are female - male plants have smaller bits. But Marchantia can also spread asexually via gemmae - clumps of cells contained in cup-like structures on the upper surface of the plant until splashed out by rain, or when older parts of the plant die off and the newer branches develop into independent plants.

Craters of the Moon, Taupo Volcanic Zone, New Zealand

[1percenthealthier]

7 WARNING Signs Your LIVER is DYING (Don't Ignore!)

[bpod-bpod]

Sense of Place

Liver cell mitochondria sense available nutrition differently depending on where in the liver the cells are

Read the published research article here

Video from work by Sun Woo Sophie Kang and colleagues

Cell Biology and Imaging Section, Thoracic and GI Malignancies Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA

Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature Communications, May 2024

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[fieriframes]

[Hepatic.]

[ihearthisto]

🐱 Kitty Liver 🐱

Check meowt!

I'm a purrfect hepatic vein surrounded by hepatic lobules!

i♡histo

This is a hematoxylin and eosin stained slice through a liver that was injected with carbon/ink prior to fixation.

The liver is compose of numerous roughly hexagonal shaped lobules. Each lobule has a venule at its center (the central vein; top right) and a series of hepatic triads at its periphery. A triad is a collection of three structures - in this case branches of the hepatic artery, hepatic portal vein and hepatic duct.

Blood in the hepatic artery (oxygenated) and hepatic portal vein (rich in nutrients absorbed from the intestines) travels in sinusoids (the many narrow white spaces in this image) towards the central vein of each lobule. On its way through the sinusoids the blood is processed by the the many hepatocytes that line this region (the pink cells). Within the sinusoids reside many liver macrophages (Kupffer cells) that phagocytose debris traveling through sinusoids. Normally these cells are invisible in standard H&E preparations but recall that this tissue was injected with ink! The ink was phagocytosed by the macrophages filling their cytoplasm with carbon so that they are now visible as black cells in the sinusoids.

Once the blood enters the central vein of each hepatic lobule they drain into the hepatic veins (kitty!) until the blood reaches the inferior venal cava.

In this way all blood, rich in raw nutrients and toxins absorbed from the GI tract is processed by the liver before it enters the systemic circulation!

Pawsitively unbeliverable!

[deepgrotto]

A queen for my Organ Girl series: Liver!

[biomedicool]

Liver Circulation - Flashcard

The liver is supplied with blood by the hepatic artery and the hepatic portal vein

branches of the hepatic artery and the hepatic portal vein distribute blood to the periphery of the liver lobules.

Blood passes along sinusoids, which are lined by hepatocytes, which perform numerous metabolic and synthetic functions. 

The processed blood passes into branches of the hepatic vein in the centre of each lobule, and eventually drains into the hepatic vein. 

The biliary system is independent of the vascular system and bile moves in the opposite direction to the blood. 

Initially it is collected in bile ductules which are surrounded by collagenous tissue, which forms part of the collagenous trabecular septum. 

The bile is collected by increasingly large trabecular ducts, which fuse to form intrahepatic ducts which finally drain into the main hepatic ducts.

[healthinnovations]

Gut microbiota that impairs normal skeletal growth identified.

Gut microbiota that impairs normal skeletal growth identified. Thoughts health innovators?

It is known that the human gut contains trillions of bacteria, known as the microbiota, which play a crucial role in digesting food and regulating the immune system. Gut microbiota also regulates immune processes that influence normal skeletal growth and maturation. However, the influence of specific microbes on immune-based osteoregulation is unknown. Now, a study from researchers at MUSC Health…

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