#ips cell immunogenicity

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New Paper on IPS Cell Immunogenicity, Clinical Insights, & Possible Solutions

New Paper on IPS Cell Immunogenicity, Clinical Insights, & Possible Solutions

Can cells produced from autologous induced pluripotent stem cells (IPSC or IPS cells) sometimes be immunogenic in patients?

This key question has remained somewhat unsettled due to varied findings over the years (e.g. see here), but many of us had generally felt in the last couple years that immunogenicity in an autologous context wouldn’t be a major problem.

This is a big deal because if human…

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