#lipid bilayers

[jonat941]

Nanobowls serve up chemotherapy drugs to cancer cells

Nanobowls serve up chemotherapy drugs to cancer cells

by American Chemical Society MAY 20, 2020

In this illustration, a nanobowl (purple semicircle) supports the structure of a liposome (blue membrane bilayer) to help keep a chemotherapy drug (red) from leaking out. Credit: Nano Letters 2020, DOI: 10.1021/acs.nanolett.0c00495

For decades, scientists have explored the use of liposomes—hollow spheres made of lipid bilayers—to deliver…

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[tsquim2]

“Microscopía” computacional de membranas celulares.

Modelo de una membrana celular idealizada, compuesta de 63 tipos diferentes de lípidos, inluyendo el colesterol, fosfatidilcolinas (PC), esfingomielinas (SM), fosfatidiletanolaminas (PE), gangliosidos (GM), fosfatidilserinas (PS) y fosfatos de fosfatidilinositol (PIPs).

Referencia: http://jcs.biologists.org/content/129/2/257

[Figura adaptada de Fig. 1A, B en http://pubs.acs.org/doi/abs/10.1021/ja507832e]

[larryhbernsteinme]

RNA polymerase – molecular basis for DNA transcription

RNA polymerase – molecular basis for DNA transcription

RNA polymerase – molecular basis for DNA transcription

Larry H. Bernstein, MD, FCAP, Curator

Leaders in Pharmaceutical Intelligence

Series E: 2; 3.1

Roger Kornberg, MD Nobel Prize in Chemistry Stanford University

Son of Arthur Kornberg, who received the Nobel Prize for DNA polymerase, Roger Kornberg spent decades on the problem of transcription of the genetic code in eukaryotic cells. Roger…

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