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Mistigram: this texty screen, a touch of Bosch at the beach, is the handiwork of @adelfaure , designed as album art for #EarthlyDelight by #Oncogenesis. This piece was included in the new music-themed MIST0224 artpack collection.

#adel faure #textmode #oncogenesis #MIST0224 #beach #heatwave #pollution #earthly delight

Unexpected Indication

Like a burly bouncer with a hidden talent for ballet, there’s more to telomeres than meets the eye. They are repeating sections of DNA that sit at the end of strands, protecting the inner regions by degrading a little each time a cell replicates. They eventually diminish sufficiently to cause cell damage as we age. It was recently discovered that, counter to previous beliefs, these lengths of DNA can code for two small proteins, VR and GL. Researchers synthesised these to study their impacts, and then found them more frequently in cancer cells (pictured, VR in green, human cancer cells in red) and in people with telomere-related diseases. A blood test for these proteins might be a route to early cancer diagnosis, and as the levels rise over time, the potent proteins might be an indicator of a person’s biological age (a more significant indicator of health than chronological age).

Written by Anthony Lewis

Image from work by Taghreed M. Al-Turki and Jack D. Griffith

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Image copyright held by the original authors

Research published in Proceedings of the National Academy of Science (PNAS), September 2023

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#science #biomedicine #telomeres #chromosomes #dipeptide #immunofluorescence #cancer #oncogenesis #ageing

Uterine adenosarcomas are an uncommon gynecological neoplasm consisting of benign epithelial and malignant mesenchymal components and usually presenting as a polypoid mass.

Adenosarcoma