Witcher 3: Wild Hunt but instead of gaining Toxicity from drinking potions, Geralt just gets progressively drunker because they all have a strong alcohol base.
This causes loss of coordination, dulling of the senses, inappropriate giggling and drunk-dialing scandalized authority figures (again). It also creates unique dialogue options that may have good or bad results.
(Cut for mild spoilers)
Good example:
Geralt: Oh man Dettlaff I’m so fuckin’ sorry about your girlfriend being so awful bro...that’s such a raw deal...you sure you don’t want to go party and forget about her instead of killing everybody in Beauclair? I mean she’s...she kinda...hates people there and wants ‘em suffering so why...*hic* why keep killing for her?
Dettlaff: *blinks and hits pause on his impending rampage* ...perhaps you have a point. *looks at Regis and side-whispers* Is he okay
Regis, *hiding an empty potion bottle behind his back* He’s simply moved by your terrible experience, I’m sure....
Bad example:
Geralt: *says anything whatsoever in Yennifer’s presence but accidentally calls her Triss in the process*