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Scientists say ‘runner’s high’ is like a marijuana high

(WP) A new study published this week in the Proceedings of the National Academy of Sciences challenges that notion and puts forth a different theory: That that “high” it could be due to different substance called endocannabinoids.

Endocannabinoids can basically be thought of as the body’s self-produced marijuana and, like cannabis, can impact a wide range of physiological processes, including appetite, pain, memory and mood.

Now the new research was only in mice, so it’s unclear how it will apply to humans, but what the researchers found is almost certainly intriguing enough to inspire followup studies.

Researchers from the Central Institute of Mental Health of the University of Heidelberg took mice and gave them running wheels. They found that after the runs, the mice were less anxious and tolerated pain better.

Then they used drugs to block the animals’ endocannabinoid system. The results were striking. The animals were as anxious after running as before running and more sensitive to pain.

“We thus show for the first time to our knowledge that cannabinoid receptors are crucial for main aspects of a runner’s high,” the researchers wrote.

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