Since you preferred I keep you anonymous, I am doing so. I protect my askers (unless they're jerks, then all bets are off).
So... you asked a good question! We actually don't have anything concrete, but a lot of speculation, and people noticing things on social media, publicity, and so forth.
I think... for Jared's sake and his friendship with Jensen... Genevieve tried to be friendly/friends with Danneel. We do know there were some events they hung out together, seemed nice to each other. But right around 2018 or so, according to those who have been in the fandom longer than me, there was something that happened. Suddenly Genevieve stopped following Danneel and vice versa. (They're back to following each other on Instagram.)
We don't know what it was though. Oh, they maintained a friendly appearance in public--Danneel even went as far as to claim that she and Jensen were good friends with the Padaleckis, but the genuine one seemed to be Jensen and Jared, not Genevieve and Danneel--but in private? Out in the wild, out in public but not a public event? Nada. Zip. Zilch.
It may be Genevieve honestly tried... but as is Danneel's history... she really can't maintain friendship with a lot of women. Oh, sure, she's "friends" with Sophia (ass-kissing for One Tree Hill) and "friends" with Hilarie (birds of a feather is the feeling I get from those two), and seemingly good friends with Bevin Prince. But a lot of Danneel's former friends? Like Elizabeth Harnois? Gone (has not been seen together in ages). Bethany Joy? Only professional and barely even that. (And I think Danneel, et al, burned that bridge with the One Tree Hill reboot without including Joy, James and CMM in that discussion.)
In all honesty, there might be a reason behind Danneel's "need" to constantly move and "reset" the energy--nobody can put up with her for long. Brief day or two, maybe a week, seemed to be it for anyone to put up with her. She's a fake, and people start to notice it.
In the fandom, people only see the surface, barely pay attention to Jensen's stories/answers about her. (Hell, his own fans barely seem to listen or care about him beyond pretty boy. Sigh.)
This answer took up more than I expected. Bottomline: I don't think they even talk to each other anymore. Probably haven't since the Ackles left Austin (to Colorado and then to Connecticut).
Jared and Jensen remain friends, but their wives definitely aren't.
(My apologies for this taking longer to answer than I promised. Thanks for being patient with me!)