Try applying these effects to your cityscape image to make it stand out:
Step 1 (skip this step if your image doesn't have any noticeable noise): Topaz DeNoise -> increase the Overall Strength slider to reduce noise caused by your camera's high ISO settings. Under Detail Recovery, increase the Recover Detail slider to recover lost details.
Step 2: Topaz InFocus -> Blur Type -> Unknown/Estimate -> increase the Blur Radius to around 4 -> increase Suppress Artifacts and then boost the Sharpness slider as deemed appropriate. The capture sharpening within the plug-in will help to make the cityscape significantly defined.
Step 3: Topaz Adjust -> increase the Regions to around 18 and then boost the Adaptive Exposure slider. For this particular effect the Brush Out tool was used to remove the exposure adjustments from the landscape where halo-ing had formed.
Step 4: Topaz Clarity -> Architecture Collection -> Cityscape I, followed by additional tweaking in High Contrast, Mid-tones and Luminance.
Step 5: Topaz ReStyle -> Architecture Collection -> apply the "Glaucous Haze" preset or a different color filter that is suiting to your image. Reduce the opacity to around 46%. Optional: change the blending mode (this feature can be found in the top right corner adjacent to the opacity slider); for this particular image the "Color" blending mode was used.
Step 6: Re-size your image if needed and make any other adjustments as desired before conducting output sharpening.
Step 7: Topaz Detail -> Creative Detail Collection -> Feature Enhancement I -> use the Effect Mask to mask out the preset from the landscape so that it is only applied to the cityscape.
Hope this gives you some ideas for your image editing workflow!