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Haiku-dn’t Think Of A Title
Sugar may be sweet But good health is much sweeter Snack at your own risk
Soda-licious & Soda-ceptive: Why You Should Think Before You Drink
From a young age, we’re taught the importance of eating right... but what about drinking right? Added sugars have snuck their way into all kinds of foods, but surprisingly, almost 50% of added sugars consumed by the average American are from drinks! The popularity and accessibility of sugar-sweetened beverages (SSBs) has given them the title of “Public Enemy #1” in the fight against obesity and related diseases.
Figure 1: (A) SSB’s include vitamin water, sport drinks, energy drinks, soda, and fruit-flavoured drinks (B) Non-SSB’s include milk, 100% fruit juice, and water.
So what actually makes SSB’s the main villain in the obesity battle, as opposed to other sugary foods?
When you eat a meal, you consume calories but also obtain a variety of nutrients and achieve a feeling of fullness. When you drink pop, juice, or any other SSB, you’re still consuming calories and sugar, but these are empty calories. This means that you aren’t achieving the same full feeling, so you’ll consume more calories later on. It’s plain to see how these extra, hidden calories can add up and lead to weight gain. 1 in 4 Americans get at least 200 calories per day from SSBs. Based on a diet of 2000 calories per day, this accounts for 10% of daily calories. When this 10% is not accounted for in the rest of the daily diet, it leads to added calories each day and ultimately weight gain and increased risk of metabolic diseases.
Consuming liquid sugars also makes them more absorbable by the body, leading to harmful metabolic effects and more fat accumulation. Natural fructose in fruits and vegetables in absorbed more slowly by the body, since other nutrients (like the fibre in apples!) are being absorbed at the same time and regulating the digestive process. Similarly with milk, the sugar absorption is slowed down due to the presence of other proteins and fats. Consequently, when you consume a sugary drink composed primarily of carbonated water and HFCS, the liquid fructose is absorbed more quickly and increases the rate of hepatic extraction of fructose, de novo lipogenesis, and production of lipids. (See The F Word for more on HFCS metabolism)
Figure 2: Representation of SSB consumption in the USA. 50% of the US population consumes an SSB on any given day, 25% of the population consumes 200 cals/day from SSBs (approximately 2 cans of soda), and 5% of population consumes at least 567 cals/day from SSBs (approximately 4 cans of soda)
With long-term studies looking at overall diet and SSB consumption of both children and adults, we are able to see the effects directly rather than making conclusions about the harm of sugar based on mice or rat response. Even though there are a lot of variables involved in human trials, research behind the effects of SSBs is still proving to have an impact on how health and nutrition initiatives are tackling the problem of obesity.
It may sound obvious that replacing SSBs with alternative beverages would improve health, but there are actually extensive studies that have been done to support the idea. From children to adults, total energy intake as well as body composition and weight have been analyzed in long-term studies with regular 24hr diet recalls and regular food frequency questionnaires (FFQs). Studies looking at risk of type 2 diabetes, stroke, high blood pressure, and fatty liver disease have also been done, but only on adults. This review paper from last May looks at research going back as far as November 2013 to summarize the data and draw firm conclusions about the impact of SSBs on health over time.
But why so much research to support such a seemingly straightforward concept?
With the rising obesity rates in Canada and the US, there is more focus on changing regulations on food labeling and marketing to help limit consumption of unhealthy foods while promoting healthy alternatives. The updated Dietary Guidelines for Americans (2015-2020 Edition) has adjusted its recommendations for sugar consumption from “cutting back on calories from sugar” to “less than 10% of calories from added sugars per day.” Drinking 1 can of pop can be enough to surpass this limit! Some physicians are advocating for warning labels, limited SSB access, and even a “soda tax” with hopes of decreasing SSB consumption. (As strange as a “soda tax” may sound, it’s actually proven to be effective in lowering SSB consumption by an estimated 12% since being implemented a year ago in Mexico. Read more about the Soda tax here.)
Personally, rather than an increase costs of SSBs with a “soda tax”, I’d like to see healthier drink alternatives lower their prices instead. There’s definitely something wrong with the fact that you can buy a 32 oz pop for less than $1, but a bottle of water can cost around $2.
What a time to be alive.
Accessible, less expensive alternatives and better education about the hidden health concerns behind SSBs makes more sense to me compared to limited access and added tax.
That brings me to why I’m so excited about all this SSB research... because it’s getting people talking! Once the Dietary Guidelines on sugar were updated in January, many major newspapers and broadcasting companies had something to say about it. This spread the word beyond the scientific community and out into the public in a way that everyone can understand.
In the end, as with most of the sugar research I’ve explored thus far, it’s important to take it all with a grain of salt. The key seems to be moderation and awareness. By being conscious of any extra sugar you’re putting in your body from SSBs and, as a result, cutting back on the extra sugar elsewhere, you should not have too much to worry about. Despite how unbiased the researchers try to be, everybody is different so there are always considerations when it comes to your dietary health and what works for you. Just be mindful, and think before you drink... because too many sugar-sweetened beverages may not be so sweet in the long run.
- Katie B
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Extra reading:
This study from last January followed 358 third graders for 6 years and examined the effects of substituting SSBs by tracking their diets and weight gain, while doing a great job accounting for variables like socioeconomic status, physical activity, pubertal status.
CNN article and NY Times Blog on the new added sugar recommendations.
Photo sources: http://www.mymacs.ca/polar-pop-1?language=en & http://www.mcdonaldsajax.com/2014/04/dollar-drink-days-are-back/
Poppin’ Some Sugar
Maybe Mary Poppins had the right idea back in 1964, but based on the recent research, some people may start looking for an alternative approach to help their medicine go down. (Though let’s not forget that moderation is key!)
Here’s a link to the movie scene if you want a little Friday afternoon throwback to some classic Disney: https://www.youtube.com/watch?v=vLkp_Dx6VdI
- Katie B
Stressing on Sucrose
As we approach the final stretch of the semester, I thought it would be fitting to talk about sugar and stress. Looking into new research on sugar consumption, I found a couple of new studies exploring how sucrose may have adverse effects on developing brains similar to the negative effects caused by early life stress. The hippocampus is the area of the brain responsible for cognition and memory, and some of its genes can be altered during times of stress as the brain is developing. These alterations to the brain early on have been shown to cause psychiatric disorders later in life. This study in particular showed that both young mice subject to stress and young mice subject to sucrose-rich diets showed a decrease in expression of multiple hippocampal genes. These include genes related to memory retention, neurogenesis, and stress response. Who knew that your sugar consumption as a kid could affect your future this much. Though its not for certain that humans have the same fate as these mice, it may very well give parents a greater incentive to ensure their children have healthy, balanced diets early in life.
(One thing’s for sure: If I were a lab mouse fated to a brain disorder, I would definitely prefer being subject to a sugar-filled diet than being subject to stress-inducing maternal neglect!)
Sugars of Fredericton
I’ve always loved photo-documentary blogs like Humans of New York and The Dogist, so I wanted to look at some sweet snacks with a similar approach. I took to the streets of Fredericton this weekend and interviewed a few foods and drinks to hear what they have to say about their sugar content.
Enjoy!
- Katie B
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“In a world of refined sugars, people sometimes forget about me. It’s a shame though. I mean, look at me! I’d say I’m a pretty good catch. I’m 40% fructose, 30% glucose, sweeter than those other guys, AND I’m not going to raise your blood sugar as much. So what if I’m a couple more calories per tablespoon… I’m worth it.” ——————————-
“People sometimes look at my label and judge me for my 25g per serving, but it’s unfair! I’m all natural!” ——————————-
“Keeping the Doctor away is tough, but someone’s got to do it. Yeah, I’ve got some sugar, but it’s not just what’s on the inside that counts in my case! My skin is full of fiber to prevent that pesky blood sugar spike! Maybe I’m not the sweetest fruit out there, but with my balance of sugar and other nutrients, I’m definitely a sweet choice” ——————————-
“People never see me coming, y’know? I mean, look at me! I’m just a beverage! But little do they know, Im packing 39g of the super sweet stuff: high fructose corn syrup.” ——————————-
“We’re great friends, but we only get together in the spring! Sugar and corn syrup might be our major ingredients, but who says you can’t treat yourself and eat some sugar in moderation.” *They all peeped in agreement* ——————————-
“I think they thought they were being clever when they put this “Natural Flavours” checkmark on my box, but it’s kind of ruined my vibe ever since. The people aren’t clueless - there’s plenty of sugar in my chocolate AND my candy coating. Pretty obvious.” ——————————-
The F-Word
Growing up with two older brothers, I was well aware at a young age of the many bad words I had to be careful not to say… but kids growing up today may have yet another bad word to worry about: Fructose.
Sugars have always caused controversy in the field of health and nutrition, but with rising rates of obesity along with other metabolic diseases, there’s a new F-word that could get you in trouble. What’s interesting is that despite how popular media often presents fructose and it’s close relative high fructose corn syrup (HFCS) as being harmful (check out this clip from the daytime talk show The Doctors) this may not be the whole truth. The fructose controversy is made clear in the scientific literature, where there is a strong divide between individuals claiming fructose is harmful and individuals challenging the data against fructose. In order to understand the argument, it’s important to look at how the various types of sugars stack up against each other. Hopefully this post will give you some insight into the research that’s out there for and against fructose consumption so you can decide for yourself if we’re really dealing with a new bad word that may have a worse consequence than just washing your mouth out with soap!
Ok, so how does fructose match up against other types of sugars?
Fructose is a monosaccharide (the simplest type of sugar molecule) naturally found alongside glucose in foods like fruits and honey, though since the 1970s it has been used to develop the corn-derived sugar high fructose corn syrup. Due to its low cost, long shelf life, and potent sweetness, HFCS has become a regularly used alternative to sucrose ever since its discovery. HFCS varies from sucrose in that rather than a disaccharide composed of one glucose molecule and one fructose molecule covalently linked, it is composed of almost equal parts fructose and glucose monosaccharides. The difference in molecular composition, as well as examples of where these sugars are found, is shown in Figure 1.
Figure 1: Molecular structures and food sources of A) fructose, B) glucose, C) sucrose, and D) high fructose corn syrup
Because the use of high fructose corn syrup in processed foods has coincided with the rise in obesity and obesity-linked diseases, researchers hypothesized a link between the two. Tests have shown that high fructose diets cause a variety of adverse effects on rats, including cardiovascular problems and metabolic syndrome, which includes increased blood pressure, a high blood sugar level, excess body fat around the waist and abnormal cholesterol levels.
Though rat studies show harmful effects of fructose, fructose advocates are calling their bluff. While it may be true that diets high in fructose negatively impacting rat health, this is not an accurate depiction of human fructose consumption because they are feeding the rats either solely glucose or solely fructose. The name high fructose corn syrup is deceiving, because it is not actually a substance high in fructose, but rather a substance containing approximately 45% fructose and 55% glucose (depending on the type.) This means that the actual effects of high fructose corn syrup are difficult to accurately measure since it’s a mixture of both the glucose and fructose monosaccharides being consumed at once.
Figure 2: Adverse effects of fructose metabolism, including uric acid production leading to increased blood pressure, G3P production leading to increase triglycerides, and a skipped regulatory step in glycolysis ultimately leading to hyperlipidemia (high fat concentration in the blood)
Researchers examining links between high fructose corn syrup and obesity have also explored how fructose is metabolized. Key factors of the fructose metabolic pathway, which are speculated to have negative effects, are highlighted in Figure 2. Fructose has been shown to stimulate glycerol 3-phosphate production in humans, which is a compound that results in free fatty acids in the body being converted to triglycerides. The extra fat stored in your body is composed of these triglycerides, which leads to increased cholesterol. Another side effect of fructose metabolism is its conversion to fructose-1-phosphate, which gives off uric acid as a by-product. Uric acid waste actually blocks a key enzyme in the body responsible for making nitric oxide, and this leads to an increase in blood pressure, which can lead to heart disease. Finally, glycolysis of fructose differs from that of glucose in that it skips an important regulatory step that results in excess fructose converting into cholesterol and triglycerides that can cause increased fat concentration in blood and increase body fat. You can read more about the metabolism of fructose here!
What’s interesting about the argument claiming high fructose corn syrup is a harmful sugar is that, as seen in Figure 1, HFCS and sucrose have almost the same molecular composition, with the exception of one bond. The covalent link between the fructose and glucose monosaccharides that form the sucrose disaccharide ends up being cleaved by an intestinal enzyme before it gets absorbed and metabolized. This means that in reality, you’re consuming the same molecules whether from a food containing natural or added sucrose or a food with added HFCS. Because of this, it appears that not only should we be mindful of HFCS consumption, but also fructose and sucrose consumption, because in any case, fructose is still being metabolized and causing the adverse effects mentioned above.
Ultimately, I believe that when it comes to a link between sugar consumption and obesity, we can fall back on the idea that it’s possible to have too much of a good thing. Regardless of how different sugars are metabolized, I think it’s pretty evident that overconsumption of any macronutrient can negatively impact the body, and with fructose metabolism, whether consumed on its own, or as part of sucrose or HFCS, there can be adverse effects on the body if we overindulge. Unfortunately, there’s still a lot to be discovered in this field if we want a concrete answer, and right now I think being educated on both sides of the F-word argument is important. Although they won’t give us any answers right away, I think the next steps in this research should involve long-term studies looking at how differences in both quantity and type of sugar consumption impact health. An 11-week trial on mice, as discussed in my last post, can give us some insight but not the whole truth of the matter.
It’s safe to say that the research has yet to convince me to completely eliminate fructose filled foods from my diet, but I’ll definitely be more aware of my intake. There may be an F-word I should work on removing from my vocabulary, but I don’t think I’ll be completely removing the F-word from my diet just yet!
- Katie B
Recent evidence suggests that fructose consumption is associated with weight gain, fat deposition and impaired cognitive function. However it is unclear whether the detrimental effects are caused by fructose itself or by the concurrent increase in overall energy intake.
In the great sugar debate there has been a lot of talk about different types of sugars having different effects on the body. Here’s a neat article in Nature comparing fructose and glucose on a few of these effects, including weight gain, fat deposition, and impaired cognitive function. Using mice as a model they were able to look at differences after 11 weeks of feeding either a glucose or fructose heavy diet. The amount of sugar given to the mice was comparable to the intake of Americans who consume high fructose diets, which seems like it should be common practice for sugar-intake studies, but is surprisingly not common! (An idea that I’ll explore further in a future post.) Some researchers speculate that it is not necessarily the fructose but rather the increase in calories that leads to weight increase in those who consume high fructose diets, so this study gave both mice groups an equal caloric intake. Interestingly enough, mice consuming fructose had increased body weight and also less physical activity after the test, though there was no impact on the brain. I thought this was a pretty cool study, as well as a sweet preview of the type of research that will be discussed in my next big post, where we’ll dive into the controversies between fructose and glucose further!
Stay tuned!
-Katie B
Labels will feature a ‘per cent daily value’ for sugar, which helps people determine if it has a lot of, or a little, sugar
Last fall, Health Canada proposed new changes to Canada’s regulations on food labels. Coincidentally, last fall I took a nutrition course here at UNB, and on the first day our first assignment was as follows: Write a letter to Health Canada giving your feedback on the proposed changes. I forgot all about this until discovering this article from last June, in which the new requirement for sugar information on food labels is discussed.
Check out the changes! I must say, I have my doubts on their choice to ignore having “added sugars” on labels, since there seems to be a big difference between natural sugars and “free sugar” (added sugars, honey, syrup, etc… which are linked to health problems.) I’ll definitely be keeping this article in mind over the course of the term, since food labels are potentially deceiving consumers in terms of sugar content. Biochemically, consuming your daily recommended intake of sugar from fresh fruit is surely much different from consuming your daily recommended intake from Pepsi and Fruit Loops!
- Katie B
A Short & Sweet Introduction
Hello sweet friends, and welcome to Sweet Talk. Before I get into the sweet stuff, I want to share a little story...
I spent my whole childhood in the same little house on the same little street in Rothesay, NB with my mom, dad, and two older brothers. From a young age, I always had an interest in food. I was that kid who would be watching the Food Network after school while the other kids were watching YTV or the Family Channel. I always loved cooking and baking, so much so that my older brothers and the other boys on my street started making fun of me and calling me Martha Stewart... *cue the sad violin music.* After my famous chef dreams were crushed, er, put on the backburner, I took a break from the cooking scene for a while… but worry not! The story has a happy ending!
Years later I found myself working at my favourite place on earth: Camp Medley. In your first year as a counsellor at Medley, you get put in the kitchen to help with the cook and assistant cook for a few weeks throughout the summer… I thought this was something I would hate, but I ended up having a great time working with the other kitchen staff prepping meals for the kids every day. I actually loved it so much that I ended up being the assistant cook for two years, and then the head cook!
[Here’s a picture of my favourite place to cook dinner for 100]
Planning nutritious menus in my time as head cook forced me to really look at ingredients and work at making meals that were tasty while still good for you. Researching healthy alternatives opened my eyes to all the controversies in the media in terms of food and nutrition. This is why I wanted to create a blog exploring sugar! There are so many different types of sugars and sweeteners out there, which made me wonder how they are affecting our bodies on a biochemical level. Over the course of the term, I aim to explore the effects of natural, added, and artificial sweeteners on various metabolic pathways in a way that the public can understand.
As a snackaholic, I’m always looking for healthier alternatives to my favourite snack foods. As a biology-chemistry student at UNB, I’m interested in the biochemical background behind certain foods as well! Though I wish the science would reveal that chocolate bars, gummy worms, and pumpkin spice lattes all contain the best possible types of sugar and that they should be consumed daily, realistically this may not be the case. At the end of the day, I hope to unravel the bittersweet truth behind the sugars we know and love to help people better understand what they’re putting in their bodies. Food has an effect on everyone, and sugar is all around us- plus I bet I’m not the only one who feels like Michelle Tanner when it comes to cookies...
So follow along as I explore the science behind sugars, and how we can all hopefully still satisfy our sweet tooth without compromising key metabolic pathways and the overall well-being of our bodies.
Talk to you sweeties soon!
Katie B