Medicine Packaging

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Bilcare points out the best ways to develop an RFP

Request for proposals (RPF) is usually put up by a pharmaceutical company having a drug product looking for a contract manufacturing site.  RPF includes all the information about the organization and time & cost involved. It is a crucial aspect that has a major effect on the relationship between the manufacturer and sponsor. The transfer of technology and the cost of commercial products can be adversely affected by a poorly organized RPF. It also has the potential to slow down the process of selecting the best manufacturer. Bilcare, a prominent name in the medicine packaging industry points out the important aspects an organization should ensure while developing a RPF.

A well organized RPF should cover all the information like the manufacturing process involved, the formula used, the use of specialized equipment, raw material and packaging components used, analytical specification & methods, the API safety data and the materials & associated grades or specifications needed. The other details include the size of the bottle and cap, the use of desiccant, the quality control testing required and the regulatory strategy.

All the outsourced activities are controlled and reviewed under the ICH Q10 guidelines. The FDA and ICH requires a technology transfer to achieve product realization through the smooth transfer of comprehensive knowledge of the process and product. Bilcare points out that communication is a crucial part of this process. It is recommended by the FDA as it acts like a quality agreement for stating the responsibilities and roles of each party.  

The company focuses on the need for ensuring environment friendly and safety measures in the process of formulization. Bilcare states that these measures can be ensured through a material safety data sheet (MSDS) and Safe Bridge Consultants Potent Compounds Safety Rating, which safeguards the manufacturing employees from all potential risks involved.

[medicinepackaging-blog]

The Medicine Packaging industry is worth $101.3 billion in the year 2015

The world Healthcare packaging market is a treasure of $101.3 billion in the year 2015. The medicine packaging experts and specialists analyzed the same by going through the market situation, trends and technology being used in the market, and predicted the forecast of the healthcare packaging industry in the year 2015.

It was found in this analysis that major factors responsible for the growth of the medicine packaging market are rapid development in the healthcare sector and medicine packaging industry along with the rising functional requirements for healthcare packaging products. Experts analyzed that the factors which contributes in increasing the demands of pharmaceutical products and services include the growing number of old people around the world, change in people’s lifestyles and frequently spreading chronic diseases. All these elements collaboratively boost the medicine packaging industry.

The experts concluded in this analysis, that despite of rapid growth of Indian and Chinese medicine packaging industries, USA will remain in the lead. The factors which contribute to the growth of these developing economies’ medicine industries are the increasing rate of standard of living and personal disposable income.

The Indian economy is doing well in the healthcare sector and medicine packaging industry, with the support of numerous anti clinical packaging specialists like Bilcare, who all are quality product and quality service providers. Bilcare is a global leader in anti-counterfeiting packaging and medicine packaging, which has numerous representative offices in more than 20 countries. The medicine packaging expert, Bilcare is globally renowned for its quality products and services, and in order to make sure about it, the firm has established many research and operation centers in developed Nations like Germany, Singapore, Us and others.

In materials healthcare packaging market, plastic is expected to stay ahead in the race because of its high level of adaptability and cost effectiveness and where glass is used for medicine packaging, it might get replaced by other substitutes like vision gain predicts and plastic.

[medicinepackaging-blog]

Importance Child Resistant Packaging

Sometimes medicine becomes the most poisoning accidents, household products and cosmetics. As the survey conducted by the World Health Organization (WHO), Child-Resistant medicine packaging is one of the best-documented solutions in preventing the accidental poisoning of children. It also observed that pharmaceutical drugs are the leading cause of non-killing poisoning in children in medium and high income Nations.

Child-resistant (CR) medicine packaging is being used to overcome the risk of poisoning in children via the ingestion of potentially hazardous items including certain prescription and over-the-counter (OTC) medications, pesticides, and household chemicals. According to the US Poison Prevention Packaging Act (PPPA), the term “Child-resistant” means that packaging is designed or constructed to be very difficult for children under five years of age to open or obtain a toxic or harmful amount of the substance contained therein within a reasonable time and easy for normal adults to use properly.

It doesn’t mean that children from this category cannot open a CR-packaging within a reasonable time. The CR-packaging is intended to be a last line of protection with safe and adequate storage of drug being the first defensive measure in harm reduction.

The CR-closure for bottles and jars is well known, so I made a selection of recent developments in CR-packaging outside the bottle and jar sphere. I have 3 CR-designs for aerosols and/or spray bottles, 2 recent launches of CR-folding cartons with blisters, a CR-solution for flexible (stand-up) pouches and a CR-blister lidding option. It will be a long story, so the 3 CR-designs for aerosols go to the next article. In this one the folding cartons, the stand-up pouch and the blister lidding.

[medicinepackaging-blog]

How to Beat Hidden Costs in medicine Packaging

Especially for anyone balancing their priorities, juggling multiple projects, and taking on increased responsibility, it can be a real challenge to identify and eliminate hidden costs like time spent on pharmaceutical packaging. Ironically, you often have to spend time just to find ways to cut time spent on a project. However, it gets easier when you know who to turn to and know how to examine the following key areas to achieve savings you can measure.

How to Save on medicine Packaging

It might be an understatement to say how incredibly valuable time is in today's business environment, but it needs to be emphasized until we all are more cognizant of opportunity costs. Since we could always use more time and opportunity to do what gets the best return, we can save both time and energy in these five key areas and get the product packaging you need for optimal function and shelf appeal.

Here are the savings we're seeking out for customers:

1. Sourcing the best packaging components or total solution from huge global network. Global networks like ours don't just spring up overnight, medicine  packaging specialists have an extensive history of growing network for the long-term. Our customers don't have to start from scratch and each of our experiences lead to your gains.

2. Sharing industry knowledge to help customers stay on top of changes in regulations and more. Whether it is a required change for child resistant packaging for products containing imidazolines or a rather obscure best practice talked about deep inside the pharmaceutical packaging industry.

3. Finding the best freight option. Make this as simple as a few questions for you and then run with it to get your product from where it starts to where it needs to arrive at the time it's needed. Always looking to save you time and deliver superior customer service, and this is a prime example of one area we do everything to deliver on that.

4. Holding network to a high set of standards to deliver the highest quality products. Global advantage is something we take much pride in, so we utilize every opportunity to bring a world-class approach.

5. Utilizing knowledge that comes from year after years of experience as a leader in the packaging industry. At Bilcare Packaging, work is a tradition handed down through the family and to extended family of employees building long-term relationships and packaging authority. Teams of experts and specialists have always worked for the long-term and lead so customers can have every advantage possible.

[medicinepackaging-blog]

Medicine Packaging Firms

Medicine packaging is a vital component of the medicine delivery system as pharmaceutical companies have to be extremely careful that their drugs reach the end user in a sterile and usable condition. The packaging has to meet stringent FDA standards, be suitable for the contents and also be easy to transport and keep on shelves, be antiseptic, tamper proof, have childproof caps at the same time being senior friendly. When  medicines have to be used in a hospital or institutional environment, they may require different packaging than when they are used by a retail customer. medicine packaging used by pharmaceutical companies Pharmaceutical companies manufacture a wide range of medicine with different delivery systems including

· Ingestible liquids

· Sprays · Drops

· Creams,

ointments and gels

· Tablets

· Gel caps

· Dispensers Often specific medicine need very special packaging – sometimes doses have to be marked, sometimes medicines have to be available in a single dose, disposable container. Other times drugs have to be dispensed in particular quantities in containers that are safe for long-term use. Medicine packaging has to be done in impermeable containers that are strong enough to keep the contents safe during handling and transport. The product should be safe from adulteration, biological contamination or physical damage. Containers may be available in

· Glass

· PVC

· PET

· Polycarbonate

· Polypropylene

· LDPE

· HDPE

· Polystyrene With advances in technology and packaging materials, you can get the right packaging for your drugs that are safe, meets all the regulatory standards and is attractive. If you need the proper packaging for your pharmaceutical products, you have come to the right place. Bilcare can easily source what you need and even suggest the correct packaging solutions for your medicine. You can design special packaging containers for your products as well and our design team is always ready to help you. What's more, we offer the best rates and friendly services – once you come to us, you will never go anywhere else.

[medicinepackaging-blog]

The result of  good-quality pharmaceutical packaging

The future of sustainable, high-quality pharma packaging depends on the development and follow-through of a strict assessment plan at all levels of an organization’s supply chain. This may mean manufacturers rely more on their packaging suppliers to promote sustainability. By using biodegradable resources, like paperboard, and by using those that support sustainability at all stages of the package lifecycle, organizations can satisfy the demands of safety-compliant and sustainable packaging.

Although challenges still exist in the pharma packaging production, innovation will continue to provide solutions for more efficient packaging and a cleaner environment. Research planning and development departments and engineers will all play a key role in the future of pharma packaging. Pharma companies will benefit from the time spent transitioning to a more sustainable model, especially as they see growing consumer satisfaction.

While the process is challenging, this shift to sustainability will positively impact the pharma industry, and any others who produce packaging, the consumer, and most importantly, the environment.

The assessment and controls depend on what your drug is—so there is not a catchall solution.

“Some drugs can be absorbed, some can be inhaled, some can be ingested, and some therapeutics can be all three. So you have to build in safety systems for all three methods of transportation into the worker’s body.” Rather than develop these safety systems for every drug individually, the guidelines suggest building a banding system that is used for all drugs.

The point of building a banding system is to categorize the risk levels of drug properties. Through a team represented by toxicology, health and safety, engineering, quality, validation, and operations, those categories are delineated into bands based on the control processes (including process, operational, engineering, and procedural controls) that the packager can implement. Examples of controls include containment systems, housekeeping, room ventilation, material transfers, and airflow controls. Then during the individual drug assessment, a drug is assigned to a band based on the comparison of the drug properties vs the band properties.

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Medicine Packaging and Supply Chain

The global pharmaceutical sector is embarking on a transformational journey in which the supply chain will play an increasing strategic role. There will be a need for greater agility and improved speed to market, while ensuring compliance with myriad regulatory requirements. This forms a challenging landscape for the global pharma industry. Consider what happens when supply chains break down: Drugs are delayed to market, customers experience poor service, security and compliance risks heighten, and a host of missed opportunities occur. So when you are selecting a medicine packager to handle your supply chain, there are several factors to consider. One is length of service.Other factors to consider include:

• Compliance with the FDA, DEA, as well as the MHRA • Employment of rigorous QA processes and cGMP quality systems • GDUFA Compliance • Serialization capabilities and experience • Capabilities which include Rest of World (RoW) packaging, Brite stock labeling and F=1 compliant packaging • Pharma packaging design services for turn-key production • Pharmaceuticals (Rx, OTC, Generic & Private Label), Nutritionals & Supplements, Beauty & Personal Care, Medical Devices, Veterinary Healthcare • Small to large batches • Cold chain storage & retain storage It is to be clear you can rely on our increased capacity, our commitment to responsive delivery expectations, and our agility in meeting the custom needs of your business. It is currently met every standard and It will continue to add capacity where needed to meet the unique specifications of our pharmaceutical customers.

[medicinepackaging-blog]

Types of Medical Packaging Missteps to Avoid

Medical device packaging engineers often face tight deadlines and budgets. So when the members of the Flexible Packaging were brainstorming recently on how to help package engineers, the group decided to focus on how they could help medicine packaging engineers minimize cycle times, iterations, and costs during new package development. Misstep 1: Missing Some Stakeholders One of the first missteps discussed in Medicine Packaging is not taking into account stakeholders “There’s a growing emphasis on eliminating all defects in the packaging process, so the challenge is designing a defect-free package that accommodates all Critical to Quality (CTQ) [attributes] while meeting design constraints such as cost and manufacturing,” he said. “Avoiding missteps starts with making sure you include all your stakeholders in the design process. Stakeholders are both internal and external, and they all have their own CTQs that need to be considered.” One example involves package dimensional tolerances. “We often see specifications that call out dimensional tolerances that may or may not be realistic. “Make sure the specification you are calling out is something that your supplier can actually manufacture. It is an example of including your external stakeholder early in the design process.” Other mistakes involve neglecting critical dimensions.

Misstep 2: Mismeasurements in Heat Sealing Mistakes in Medicine Packaging can also be made during heat-sealing processes. There are several misconceptions when it comes to parameter measurements and machine set up. One is assuming “that setting and actual sealing conditions are the same,” he said. For instance, there can be differences between the temperatures of the gauge versus the actual temperature of the platen surface, he said. Also, there can be differences in dwell-time measurements depending upon when the sealer activates the timer—is it when the platen begins to move or when it is closed and pressure begins? Misstep 3: Misunderstanding Distribution's Effects And missteps can also occur when distribution’s influence on package performance isn’t considered. One common misstep is to use a pouch that’s too large for a folding carton, explained Russell Darley, R&D Manager for Sealed Air Medical Applications. “To fit the pouch in the carton, the pouch must be folded several times; we call this creating a compound fold,” he said. “Multiple folds in a material can create material stress points, which during distribution events like vibration, impact, or free-fall drops can result in abrasion, flex cracking, pin holes, and material separation.” Using pouches and cartons that aren’t appropriately matched can be the outcome of programs that use a one-size-fits-all approach to packaging. As a result, they might not select the appropriate distribution simulation protocol and could see damage in the field, a poor product-to-packaging ratio, or experience other missteps. He offered a few key recommendations on how to better understand such channels. “Spend time out in the field following your distribution channel, map the process, talk to employees, and make observations.

[medicinepackaging-blog]

Medicine Packaging Challenges

There is a growing focus in the medicine packaging  on producing environmentally sustainable products. Increasingly consumers, and by extension retailers, are demanding the items they purchase have as little impact on the environment as possible. In fact, 71% 71 percent of people are influenced to purchase paper and packaging products based on sustainable attributes, according to a recent survey by Asia Pulp and Paper (APP). Pharmaceutical Packaging challenges   Traditionally, pharmaceutical companies were more concerned about manufacturing and supplying costs than about eco-friendliness, but with the growing pharmaceutical market, companies are now expected to be more transparent in business practices, including the downstream role they play in impacting the environment. Ultimately this means packaging is sourced and made from more sustainable materials—with the goal of less packaging in general.

Utilizing sustainable medicine packaging can be a challenge for everyday packaging needs, but even more so in the pharmaceutical industry where government safety regulations and patient usability take precedence. While consumers and retailers are shifting to a more environmentally conscious mindset, they still expect pharma companies to adhere to safety regulations and manufacture high-quality packaging for their products. Although challenges still exist in the medicine packaging production, innovation will continue to provide solutions for more efficient packaging and a cleaner environment. According to Bilcare, Research planning and development departments and engineers will all play a key role in the future of pharma packaging. Pharma companies will benefit from the time spent transitioning to a more sustainable model, especially as they see growing consumer satisfaction.

[medicinepackaging-blog]

Medicine Packaging Innovations

Bilcare Research is a leading full-service provider in the field of Medicine Packaging. As a global supplier with single-source capabilities, we offer a comprehensive range of pharmaceutical packaging solutions, from product-specific research to brand-building materials and design. It is our aim to innovate and develop pioneering packaging solutions to meet the complex needs of the pharmaceutical industry. With our integrated services, we enable clients to focus on their core business, i.e. development of new drug molecules, formulation development, manufacturing and marketing while we partner with them in the area of drug stabilization and protection. We help customers capitalize on upcoming trends, through products that maximize the commercial potential and efficacy of drugs.

 Our strength lies in the powerful synergy of our research capabilities, state-of-the-art design and manufacturing facilities and commitment to create sustainable competitive advantages for our customers. Our competency in developing specialty packaging material and designs helps customers in addressing compliance and counterfeit concerns. Today, Bilcare Research is a market-leading supplier of specialty primary packaging for pharmaceutical products. We have been honoured by the Organization of Pharmaceutical Producers of India (OPPI) Award for achieving remarkable success in providing novel packaging alternatives and services to the pharmaceutical sector for two consecutive years.