Untitled

[menopaused]

Stem cell therapy for ovarian rejuvenation

[menopaused]

β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs

Oocyte senescence alters the shape and function, thereby weakening the fertilization potential. Nicotinamide mononucleotide (NMN) reverses a

β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs

[menopaused]

Nicotinamide Mononucleotide improves oocyte maturation of mice with type 1 diabetes - Nutrition & Diabetes

The number of patients with type 1 diabetes rises rapidly around the world in recent years. Maternal diabetes has a detrimental effect on re

NMN supplementation improved the oocyte quality by rescuing the actin dynamics, reversing meiotic defects, improving the mitochondrial function, reducing ROS level, suppressing DNA damage and restoring changes in histone modifications of oocytes collected from the mice with diabetes

[menopaused]

NMN & egg quality

[menopaused]

The stromal microenvironment and ovarian aging: mechanisms and therapeutic opportunities - Journal of Ovarian Research

For decades, most studies of ovarian aging have focused on its functional units, known as follicles, which include oocytes and granulosa cel

pirfenidone and BGP-15 extends ovarian lifespan in mice

[menopaused]

Synthetic human embryos created in groundbreaking advance

Exclusive: Breakthrough could aid research into genetic disorders but raises serious ethical and legal issues

human embryo-like models

[menopaused]

(PDF) Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial

PDF | Aging is a major risk factor for the majority of human diseases, and the development of interventions to reduce the intrinsic rate of

Topical Rapamycin

[menopaused]

Introduction to AAV Gene Therapies

Small-scale successes in rare disease treatments prime large-scale industry innovations.

AAVs

[menopaused]

In vitro maturation (IVM) of human immature oocytes: is it still relevant? - Reproductive Biology and Endocrinology

In vitro maturation (IVM) of human immature oocytes has been shown to be a viable option for patients at risk of ovarian hyperstimulation sy

In vitro maturation

[menopaused]

Rapamycin slows aging in mice

[menopaused]

mTOR inhibition improves immune function in the elderly

[menopaused]

(PDF) mTOR inhibition improves immune function in the elderly

PDF | Inhibition of the mammalian target of rapamycin (mTOR) pathway extends life span in all species studied to date, and in mice delays th

mTOR inhibition extending lifespan in mice

[menopaused]

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

In patients with type 2 diabetes, intensive blood-glucose control with insulin or sulphonylurea therapy decreases progression of microvascul

Metformin

[menopaused]

#123 - Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and metformin—longevity, immune enhancement, and COVID-19 - Peter Attia

“I think what the mTOR inhibitors are doing is not stopping people from getting infected [with a virus], but if you get infected, there's a

mTOR, Rapamycin, Metformin

[menopaused]

#123 - Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and metformin—longevity, immune enhancement, and COVID-19 - Peter Attia

“I think what the mTOR inhibitors are doing is not stopping people from getting infected [with a virus], but if you get infected, there's a

Rapamycin, mTor, Metformin

[menopaused]

Dogs owners are feeding their dogs cheap pills to help them live longer — if it works, it could be an anti-aging fix for people too

Dogs across the US are taking the drug rapamycin to see if it helps them live longer and stay healthier in old age. Dog owners think it's wo

Rapamycin trial in dogs

[menopaused]

People are taking a cheap drug to try reverse-age their ovaries — and cheat their 'biological clock'

Rapamycin, a drug that's usually used to slow down tumor growth and improve transplant outcomes, could also be a fountain of youth for ovari

Rapamycin trial for ovarian reserve