Schistosomiasis is a chronic tropical disease that is contracted after Schistosoma haematobium parasite larvae pass through the skin in contact with water. In Benin, S. haematobium schistosomiasis is still one of the most widespread and neglected human parasitic infestations. The objective of this study is to determine the prevalence of urinary schistosomiasis in Ahomey-Lokpo in the commune of Sô-Ava. This prospective and descriptive study was conducted on 104 randomly selected inhabitants aged 2 to 75 years. It consisted of the collection of urine samples and their macroscopic examination (urine color) and microscopic examination (presence of S. haematobium eggs)., Each individual whose urine was collected was subjected to a questionnaire. In order to compare the averages, excel software was used for data analysis. This study revealed that several factors such as gender, age and especially occupation favor or not schistosomiasis. Among the respondents, men are more infested (41%) than women (26%) because of their profession. The results showed that 78.32% of people who have haematic urine, 76.71% of those who have dysuria, 75.11% of those who experience abdominal pain, and 69.88% of those who experience burning on urination are infested. The Sô River and the swamps are real sites of schistosomiasis transmission infestation. The majority of the people who practice their daily activities there are infested.