Aprepitant API
Aprepitant API is an active pharmaceutical ingredient (API) used in the manufacture of Aprepitant, a prescription medication for the prevention and treatment of nausea and vomiting caused by chemotherapy and surgery. Aprepitant is a neurokinin-1 receptor antagonist, which means that it blocks the action of substance P, a neurotransmitter that is involved in nausea and vomiting.
Aprepitant API is a white to off-white powder that is insoluble in water. It is typically manufactured using a multi-step chemical synthesis process. Once the API is manufactured, it is formulated into finished dosage forms such as tablets, capsules, and injection solutions.
Aprepitant API is a potent drug substance, and its manufacture and use is subject to strict regulatory requirements. In the United States, Aprepitant API is manufactured by Merck & Co.
Here are some additional details about Aprepitant API:
CAS number: 170729-80-3
Molecular formula: C23H31FN4O2
Molecular weight: 427.50 g/mol
Melting point: 118-122 °C
Solubility: Insoluble in water, soluble in organic solvents such as ethanol and acetone
Aprepitant API is a complex molecule, and its synthesis requires specialized equipment and expertise. It is important to note that Aprepitant API is a prescription drug, and it should only be used under the supervision of a qualified healthcare professional.
Aprepitant API is an important drug that is used to help millions of patients avoid the nausea and vomiting associated with chemotherapy and surgery. It is an important part of the effort to provide high-quality cancer care to patients.