#aurigene

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AUPM 170, CA 170, PD-1-IN-1

AUPM 170, CA 170, PD-1-IN-1

(2S,3R)-2-(3-((S)-3-amino-1-(3-((R)-1-amino-2-hydroxyethyl)-1,2,4-oxadiazol-5-yl)-3-oxopropyl)ureido)-3-hydroxybutanoic acid Molecular Weight (MW) 360.33Formula C12H20N6O7CAS…

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AUR 101

AUR 101 AUR 101 AUR101-201 ANTIINNFLAMATORY AUR-101, a ROR gamma inverse agonist for autoimmune disorders like psoriasis AUR-101 is an ROR-gammaT inverse agonist in phase II clinical development at Aurigene for the treatment of patients with moderate-to-severe chronic plaque-type psoriasis. DrugsAUR 101 (Primary)IndicationsPlaque psoriasisFocusAdverse reactions; First in…

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XL 114, AUR 104

XL 114, AUR 104

N[C@@H](CO)c1nc(on1)[C@@H](NC(=O)N[C@H](C(=O)O)C(C)O)CC(N)=O (2S)-2-[[(1S)-3-amino-1-[3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl]-3-oxopropyl]carbamoylamino]-3-hydroxybutanoic acid CAS 2305027-62-5 C12 H20 N6 O7, 360.32Threonine, N-[[[(1S)-3-amino-1-[3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl]-3-oxopropyl]amino]carbonyl]-,…

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Curis and Aurigene's CA 4948, AU 4948

Curis and Aurigene’s CA 4948, AU 4948

Example 13 WO2015104688 6-(6-aminopyridin-3-yl)-N-(2-morpholin-4-yl-1,3-benzothiazol-6-yl)pyridine-2-carboxamide Molecular Formula: C22H20N6O2S Molecular Weight: 432.4982 g/mol 1428335-77-6 [2,​3′-​Bipyridine]​-​6-​carboxamide, 6′-​amino-​N-​[2-​(4-​morpholinyl)​-​6-​benzothiazolyl]​- PROBABLE STRUCTURE Example 1…

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Curis and Aurigene's CA 4948, AU 4948

Curis and Aurigene’s CA 4948, AU 4948

  CA 4948, AU 4948,AU-4948, CA-4948

STRUCTURE AND SYNTHESIS COMING……..

Company Aurigene Discovery Technologies Ltd. Description Oral IL-1 receptor-associated kinase 4 (IRAK4) inhibitor Molecular Target Interleukin-1 receptor-associated kinase 4 (IRAK4) Mechanism of Action Therapeutic Modality Small molecule Latest Stage of Development Preclinical Standard Indication B cell lymphoma…

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CFG 920, Novartis Scientists team up with Researchers at Aurigene, Bangalore, India,

CFG 920, Novartis Scientists team up with Researchers at Aurigene, Bangalore, India,

CFG920, Inhibitor Of Prostate Cancer With Fewer Cardiac Side Effects Cas 1260006-20-9 Novartis Target: CYP17/CYP11B2 Disease: Castration-resistant prostate cancer MF C14H13ClN4O MW: 288.0778 Elemental Analysis: C, 58.24; H, 4.54; Cl, 12.28; N, 19.40; O, 5.54 Steroid 17-alpha-hydroxylase inhibitors CFG920 is a CYP17 inhibitor, is also an orally available inhibitor of the steroid…

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CFG 920, Novartis scientists team up with researchers at Aurigene, Bangalore, India,

CFG 920, Novartis scientists team up with researchers at Aurigene, Bangalore, India,

CFG920, INHIBITOR OF Prostate Cancer With Fewer Cardiac Side Effects

Cas 1260006-20-9

Novartis Target: CYP17/CYP11B2 Disease: Castration-resistant prostate cancer

MF C14H13ClN4O MW: 288.0778

Elemental Analysis: C, 58.24; H, 4.54; Cl, 12.28; N, 19.40; O, 5.54

Steroid 17-alpha-hydroxylase inhibitors

CFG920 is a CYP17 inhibitor, is also an orally available inhibitor of the steroid…

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AUNP-12 from Aurigene Discovery Technologies Limited

AUNP-12 from Aurigene Discovery Technologies Limited

    AUNP-12

AUR-012; Aurigene-012; NP-12, Aurigene; PD-1 inhibitor peptide (cancer), Aurigene; PD-1 inhibitor peptide (cancer), Aurigene/ Pierre Fabre; W-014A

  Company Aurigene Discovery Technologies Ltd. Description A programmed cell death 1 (PDCD1; PD-1; CD279) peptide antagonist Molecular Target Programmed cell death 1 (PD-1) (PDCD1) (CD279) Mechanism of Action Programmed cell death…

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