Diabetes is a complex metabolic condition that affects the glucose homeostasis of the human body. Inflammation has been significantly associated with diabetes pathogenesis and so makes this area a popular target for the prevention and treatment of these metabolic abnormalities. In this study, we have evaluated the anti-inflammatory and anti-diabetic properties of polar methanol (SB1M) and non-polar hexane (SB1H) extracts of a sea cucumber, B. argus, via inhibition of albumin denaturation assay, starch-iodine and glucose-uptake assay by yeast cells assays. Whilst there was no anti-inflammatory action observed in SB1H extracts, the SB1M showed anti-inflammatory potential (84.70±1.9% to 100±1.11%) with comparable activities with a known anti-inflammatory drug Flanax (Naproxen) (p