Long Term Health Problems Related To Vitamin B12 Deficiency
Research is now delving deeper into a number of health related illnesses that could be directly or indirectly linked to a Vitamin B12 deficiency. Some of these illnesses are age related macular degeneration, neural tube defects, cardiovascular disease, cognitive decline, osteoporosis and other age related declines.
Age related macular degeneration (AMD):
Vitamin B12 deficiency has been associated with the development of age related macular degeneration (AMD) and risk of frailty, both leading causes of disability in the elderly.
Neural tube defects (NTD):
Low vitamin B12 status has been postulated as a potential risk factor for neural tube defects (NTD) since vitamin B12 inhaler acts as a cofactor for methionine synthase in the folate cycle. When vitamin B12 supply is low, the folate needed for DNA synthesis remains trapped in the methylation cycle and cell replication is impaired. The studies consistently report a 2-4 fold increased risk of NTD with low vitamin B12 status. The studies were undertaken in a range of population groups including those that are exposed to folate fortified foods, as well and non-fortified populations.
Osteoporosis:
Dietary factors associated with the development of osteoporosis include inadequate protein, calcium and vitamin D. More recently, there has been interest in the effect of other nutrients, including vitamin B12 vape pen on bone health.
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