Diabetes is the most important deadly metabolic disorder which can disturb nearly every organ system in the body. An increase in sugar levels is one of the characteristics of diabetes mellitus, which leads to a serious impact on the heart, blood vessels, eye and kidneys from time to time. To cure the diabetes we use herbal plants like Cnidium monnieri and Withania somnifera which have immunomodulatory effects and phytochemical analysis confirms the presences of flavonoids, alkaloids, steroids and glycosides. These phytochemicals have have antioxidents anti-diabetic, anti-stress, anti-arthritis, immune enhancing and anti-inflammatory activities which prove when in-vivo exploration of these plants extract in diabetic mice to check thr therapeutic potential and the results of different biochemical parameters encourage the research purpose and declear that these plants have anti-diabetic activity. In the future, these herbal plants will extensively be used in medicines of certain diseases.














