#four-stranded

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I-MOTIF DNA

I-motif DNA (Intercalated motif), is a type of deoxyribonucleci acid that is found in cell nuclei and was discovered in 2018. “I-motifs are four-stranded quadruplex structures formed by cytosine-rich DNA, similar to the G-quadruplexstructures that guanine-rich DNA forms. C-rich DNA regions are common in gene regulation portions of the genome. Recently, i-motifs were discovered in human cells and…

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New Twisted ‘Knot’ DNA Structure Identified Inside Human Cells

New Twisted ‘Knot’ DNA Structure Identified Inside Human Cells

In a first, researchers at Garvan Institute of Medical Research, Australia have identified a new DNA structure inside living human cells.  Known as the intercalated motif (i-Motif), the newly identified structure looks poles apart from the iconic double helix shape everyone associates with DNA. ”When most of us think of DNA, we think of the double helix,” says Associate Professor Daniel Christ…

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