#gp120

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Tony Fauci Used Tax Payer Dollars to Engineer HIV GP-120 into SARS-2 Spike

Tony Fauci used $51 million of US taxpayers' dollars to patent HIV GP120 and engineer HIV GP120 into SARS-CoV-2 spike nanoparticles. Why are

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mRNA Is "Natural Born Killer" Says Drug Inventor Dr. Richard Urso w/ Dr Kelly Victory – Ask Dr. Drew

Dr. Richard Urso is an outspoken critic of mRNA treatments for COVID-19 and the dangers of its lipid nanoparticles. He has widely encouraged the use of exist...

LNP & mRNA Is "Natural Born Killer" Says Drug Inventor Dr. Richard Urso w/ Dr Kelly Victory – Ask Dr. Drew

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During the development of a vaccine to protect against the Sars-CoV-2 virus, it became apparent that one vaccine in development (Australia)

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BREAKING--SARS-CoV-2 Infection and COVID-19 Vaccination Associated with False Positive HIV Tests

Multiple Studies Converge on New Clinical Conundrum

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HIV Aşısında Büyük Gelişme

HIV Aşısında Büyük Gelişme

HIV Aşısında Büyük Gelişme Deneysel aşamada olan bir HIV aşısı gönüllüler üzerinde yürütülen çalışmada %97’sinde antikor oluşturdu. Bilim insanları 36 kişi üzerinde denen aşıların etkinliği konusunda çalışmanın çok dar olmasından dolayı araştırmacılar temkinli davranıyor. Ayrıca aşının çok az bir yan etkisi olması da ayrı bir sevindirici haber. HIV Aşısında Büyük Gelişme  2 ay arayla 2 doz…

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Shen et al.: "ACE2-independent infection of T lymphocytes by SARS-CoV-2; confirmed that SARS-CoV-2 viral antigen could be detected in patien

& the infectious virus could also be detected from viral antigen-positive PBCs; next prove that SARS-CoV-2 infects T lymphocytes, preferably

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T-cell recovery and evidence of persistent immune activation 12 months after severe COVID-19

Abstract

Background

T-cell lymphopenia and functional impairment is a hallmark of severe acute coronavirus disease 2019 (COVID-19). How T-cell numbers and function evolve at later timepoints after clinical recovery remains poorly investigated.

Methods

We prospectively enrolled and longitudinally sampled 173 individuals with asymptomatic to critical COVID-19 and analyzed phenotypic and functional characteristics of T cells using flow cytometry, 40-parameter mass cytometry, targeted proteomics, and functional assays.

Results

The extensive T-cell lymphopenia observed particularly in patients with severe COVID-19 during acute infection had recovered 6 months after infection, which was accompanied by a normalization of functional T-cell responses to common viral antigens. We detected persisting CD4+ and CD8+ T-cell activation up to 12 months after infection, in patients with mild and severe COVID-19, as measured by increased HLA-DR and CD38 expression on these cells. Persistent T-cell activation after COVID-19 was independent of administration of a COVID-19 vaccine post-infection. Furthermore, we identified a subgroup of patients with severe COVID-19 that presented with persistently low CD8+ T-cell counts at follow-up and exhibited a distinct phenotype during acute infection consisting of a dysfunctional T-cell response and signs of excessive pro-inflammatory cytokine production.

Conclusion

Our study suggests that T-cell numbers and function recover in most patients after COVID-19. However, we find evidence of persistent T-cell activation up to 12  months after infection and describe a subgroup of severe COVID-19 patients with persistently low CD8+ T-cell counts exhibiting a dysregulated immune response during acute infection.