EvolutionaryScale Launches With ESM3: A Milestone AI Model For Biology
EvolutionaryScale, a top AI research lab in biology, has unveiled ESM3, a cutting-edge AI model that can make brand-new proteins. This groundbreaking model created a fresh Green Fluorescent Protein (GFP), a process that would typically require 500 million years of evolution. ESM3 gives scientists the ability to prompt and design proteins, improving their use in drug discovery, materials science, and carbon capture.
The team at EvolutionaryScale are trailblazers in using AI in biology, having previously created ESM1, the first transformer language model for proteins. The ESM models have led to major scientific discoveries, such as advancements in protein folding that revealed the structures of millions of metagenomic proteins. These models have been crucial for scientists worldwide in modeling and understanding proteins.
ESM3, trained with 1 trillion teraflops on a dataset of 2.78 billion proteins, is the first generative model for biology that considers the sequence, structure, and function of proteins all at once. This feature enables scientists to comprehend and produce new proteins, essentially making biology programmable. Alexander Rives, co-founder and chief scientist of EvolutionaryScale, emphasized that ESM3 is a step towards a future where AI is a key tool in biological engineering.
ESM3 has the potential to speed up discoveries in various fields, from developing new cancer treatments to creating proteins for carbon capture. By creating a new GFP, ESM3 simulated 500 million years of evolution, proving its ability to generate complex proteins essential for molecular biology.
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