Ω CONOTOXIN GVIA
https://www.difficultpeptide.com/products/conotoxin-gvia/
Ca2+ channel blocker (N-type), Synthetic toxin originally isolated from Conus geographus. Specific blocker of Cav2.2 (N-type) Ca2+ channels. Binds to the Cav2.2α1 subunit (α1B) and its action is only partially reversible.
SPECIFICATION OF Ω CONOTOXIN GVIA
Product Name: ω-conotoxin GVIA (omega-Conotoxin GVIA, Ca2+ channel blocker (N type))
CAT.#: C1030-V
CAS N0.: 106375-28-4
Sequence: CKSXGSSCSXTSYNCCRSCNXYTKRCY (Modifications: C-terminal amide; X-4 = Hyp; X-10 = Hyp; X-21 = Hyp; Disulfide bonds: 1-16, 8-19, 15-26)
Purity: > 96%
Solubility: Soluble in water
Form/State: Lyophilized powder
Molecular weight: 3037.40
Molecular formula: C120H182N38O43S6
Source: Synthetic peptide
Shipping and storage: Shipped at room temperature. The product, as supplied, can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Storage of solutions: Up to two weeks at 4°C or three months at -20°C.
APPLICATION OF Ω CONOTOXIN GVIA
ω-conotoxin GVIA is a 27-amino acid peptide isolated from the venom of the marine cone snail Conus geographus, which specifically inhibits CaV2.2, are promising scaffolds for novel analgesic.