Hematologic and biochemical studies of birds infected with gastrointestinal parasites (helminths-eimeria) mono- and associatively were carried out in Mountain-Shirvan economic region. For this purpose, the blood of 230 diseased and 20 healthy birds was examined. Serological and biochemical studies were conducted in birds monoinvasion with Capillaria obsignata. Serological studies were also carried out in birds infected with helminths and eimeria in associative invasion. In birds associative invasion was noted with parasites Capillaria obsignata, Raillietina tetragona, Heterakis gallinarum helminths and primary intestinal parasite – E. acervulina. For comparison, serologic studies were performed in healthy birds. In sick birds with monoinvasion, the mean difference of hematologic blood parameters – PCV, RBC, MCV, MCH – was relatively decreased, and WBC, MCHC, neutrophils, lymphocytes and monocytes – relatively increased. The mean difference of hematologic blood parameters in healthy and diseased birds with monoinvasion did not differ significantly in PCV, RBC, WBC, WBC, MCV, neutrophils, lymphocytes and eosinophils (p > 0.05). The mean difference of hematologic blood indices in diseased birds with associative invasion – PCV, RBC, MCV, MCH – was sharply decreased, WBC, MCHC was relatively increased, and neutrophils, lymphocytes and monocytes were sharply increased. The mean difference of hematological blood parameters in healthy and diseased chickens with associative invasion was significantly different in PCV, RBC, WBC, MCV, neutrophils, lymphocytes and eosinophils (p < 0.05). Mean values of blood biochemical parameters in healthy birds and birds with monoinvasion did not differ significantly (p >0.05). Blood biochemical parameters in birds with associative invasion differed significantly. Differences were observed in ALT, ALP, total protein and glucose (p < 0.05). In birds with associative invasion, the mean values of ALT, ALP and total protein were higher, and the mean value of glucose was lower.
