Typhoid fever, caused due to Salmonella Typhi (S. Typhi), is considered as one of the deadliest diseases, and a serious public health problem around the world. The prevalence of typhoid fever in city of Saidu Sharif Sawat, Khyber Pakhtunkhwa province of Pakistan was investigated in this study from October 26, 2017 to February 25, 2018. The blood samples of 400 patients of age group 1- 50 years old were used for clinical diagnosis applying widal test and their results were compared for analysis. A total of 76 patients were found positive of S. Typhi. The ratio of typhoid occurrence in males (66%) was found higher as compared to typhoid positive cases of females (34%). The ratio of typhoid patients was greater in young people having ages between 11-30 years. This study provides significant statistics regarding net incidence of typhoid in the city of Saidu Sharif Sawat that would help in proposed future health policies. Preventive strategies such as immunization programs, improved sanitary standards, clean water supply and proper sewerage system should be the focus of typhoid control in cities like Saidu Sharif Sawat.














