As someone who used to be a huge husk3rdu$t fan when the pilot first came out I heavily dislike the ship in the actual series because of the way the characters are written.
Angel Dust sexually harasses Husk, which to be fair is something he also did in the pilot. However in the show after Husk rejects his """advances""" he throws a glass bottle that nearly hits Husk in the face and never apologizes for it.
Husk, who may I add by the new canon of the show used to be an Overlord who sold his soul to keep his power (which he obtained by exploiting others), calls Angel a loser when he knows he is an SA victim and even tries to compare his situation with Alastor to the one Angel Dust has with Valentino.
Outside all of this another reason is that the relationship feels so forced. Viv doesn't know how to write actual chemistry between two characters so, instead to make you ship two characters she will make all of the relationships sorrounding said characters awful and/or nonexhistant.
In the pilot there is nothing to suggest Alastor owns Husk soul to the point when first watching it I got the impression Husk only owed a favor to Alastor (which acourding to kendraws, who wrote the pilot for Hazbin, is how he inteded their dynamic to be).
In the show we find out Husk sold his soul to Alastor that forces him to work at the hotel. This change is forced and was obviously done to draw a parallel between him and Husk so that the audience would ship them. I don't hink it's a coincidence that in the next episode Alastor treathens Husk. It feels like the writers had the sudden relization that in order for us to know Alastor is abusive towards Husk they had to gives us some actual examples.
On the scene itself it feels so out of character for Alastor, why would someone that is inteded to be a master manipulator, who despite knowing how powerful he is prefers to use his own brain, completly lose their temper and act so violent at such a minor inconvenience, wouldn't it make more sense for him to try and manipulate Husk by guilt tripping him? The real answer here is that the authors simply wanted to push a parallel between the scene were Valentino treathens Angel and Alastor treathening Husk. Even Loser Baby tries to draw a parallel between the two.
Everyone already pointed out how Cherri Bomb was turned into a jerk in the main show and shown barely interact with Angel to push his relationship with Husk as more important but something similar can be said for Sir pentious.
You know how the show wants us to believe Husk, Angel dust and Sir pentious are great friends after their time spent at the hotel, despite never having them actually bond together? Well it's because they, didn't want us to get attached to any other relationship other than husk3rdu$t so they just decided to never show the two interact, otherwhise if Sir pentious had an actual reason to care about Husk and Angel than people might start shipping him with one of the two, or even both.
It sucks to see how badly this dynamic has fallen for me since the pilot I don't think I have ever been so dissapointed to see a fanon ship I enjoyed become canon. I have no interest in the whole "will they won't they" that the show tries to ricreate because viv herself already confirmed husk3rdu$t will be a slowburn romance.