Types of immunity and immunosuppressant drugs
Immune system is a group of organs, tissues, cells, molecules that help defend the body against harmful invaders these substances include bacteria, fungi, parasites, viruses and other foreign macromolecules.
Functions of immune system: Destroy pathogens, detect and kill abnormal cells, remove dead cells and cell debris from the body.
Basic types of immunity are Adaptive immunity and Innate immunity.
Innate immunity: Protection against infection before it exists it has first line defense and second line defense.
first line defense:skin, mucous, genitourinary tract, saliva, lacrimal apparatus.
Chemical: sebum, perspiration, gastric juice urine.
Second line defense: phagocytosis, inflammation, interron.
Adaptive immunity: Adaptive immunity involves specialized immune cells and antibodies that attack and destroy foreign invaders and are able to prevent disease in the future.
Parts of immune system: Primary and Secondary.
Cells of immune system: lymphocytes and antigen presenting cells.
Auto-immune diseases: type 1diabetes, rheumatoid arthritis, psoriasis, multiple sclerosis, systemic lupus erythema tosus, inflammatory bowel disease, Hashimoto’s thyroiditis, celiac disease.
Autoimmune diseases can be treated with non-steroidal anti-inflammatory drugs like ibuprofen, naproxen and immune suppressing drugs.
In some cases, the immunity of a body has to supress for that immunosuppressant drugs are recommended Immunosuppressants stop your immune system from damaging healthy cells and tissues. People with organ transplants and stem cell transplants take these medicines to prevent transplant rejections. immunosuppressant drugs which are commonly used are corticosteroids: prednisolone, prednisone, budesonide. calcineurin inhibitors: cyclosporine, tacrolimus. IMDH inhibitors are Azathioprine, mycoplate. Monoclonal antibodies are basiliximab, daclizumab.