I don't think David Messina groks how to use inner panels.
An inner panel focuses the viewer on one subject in a larger shot.
On the left page, the inner panels try to focus us on Angel's journey down the spiral staircase, but it seems off. Its hard to describe why. I think it's because it's trying to focus our attention on one area of a larger piece, but Angel only exists in that panel, he's cut off at the borders. It's trying to be a regular panel and an inner panel at the same time.
On the right page, there's an inner panel that's correctly done, but then it's repeated. Initially I thought it was a second inner panel, but it's not. I don't like it.
Messina has done a lot of great work on the rest of Angel, so this is a rare misstep.
From ANGEL: THE CURSE, by Jeff Mariotte and David Messina.