#janelia

[themoonstonechronicler]

warmup fanart for @the-forever-day-official webcomic(everyone go read)! Amelia first(feat ray, yes ik ravens are bigger than that but i didnt wanna), then Jane and amelia kissing because i think they both really need it(idk how to draw kissing sorry)

[bpod-bpod]

GAL Pals

Scientists often turn to the fruit fly Drosophila for its relatively simple (yet similar) tissues to our own. But peering into its brain is still mind-boggling. Over 8 years, researchers at The Flylight Project captured thousands of images of fly brains, while developing a genetic tool to tease these neuron tangles apart. By genetically modifying the flies’ DNA, they watch as specific enhancers help to switch on a gene called GAL4, lighting up each neuron with a random or stochastic combination of colourful fluorescence. Comparing these patterns in different cells allows the team to specifically label individual neurons (seen here in rainbow colours) – their branching forms revealing circuits within and between brain regions. The results of this painstaking work, involving 5000 different strains of fly, is now available as a public resource, aiding geneticists and brain researchers around the world.

Written by John Ankers

Image from work by Geoffrey Wilson Meissner and colleagues

Janelia Research Campus, Ashburn, VA, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in eLife, February 2023

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[themoonstonechronicler]

#janelia forever

charaters from the Forever Day webcomic! check it out at @the-forever-day-officialday

[bpod-bpod]

Wiring a Fly

Brains are complicated. Really complicated. In order to understand more about how these complex organs work, researchers are creating detailed ‘wiring diagrams’, or connectomes, which trace all the connections between nerve cells in an organism’s brain. Even for simple creatures like fruit flies, the task of creating a detailed connectome is enormous: tracing all the connections would take a team of 250 scientists two decades to complete. To speed things up, neuroscientists at the Janelia Research Campus in Virginia have teamed up with data scientists at Google. They’ve been using the latest image analysis technology to trace millions of connections between 25,000 nerve cells in a fruit fly brain, creating this dazzling image. It’s the most detailed fly connectome ever generated, covering important areas involved in learning, memory, smell and navigation. The entire fruit fly brain contains around 100,000 nerve cells, so they’re hoping to complete the job by 2022.

Written by Kat Arney

Image/video from the FlyEM/Janelia Research Campus

FlyEM/Janelia Research Campus

Image/video copyright held by the FlyEM/Janelia Research Campus

Research published in BioRXiv, January 2020

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[bpod-bpod]

Mouse Nous

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The brain is home to millions of neurons – their different tree-like structures branch across brain areas in a diverse 'forest' of connections, helping to process information, coordinate our actions and form memories. Using viruses to light up individual mouse neurons, The MouseLight Project is building a 3D model of the brain, piecing together microscopy images of glowing cells using algorithms to map out their tracks. Recently passing the 1000-neuron mark, the project reveals some brain areas have groups of similar neurons, while other regions are peppered with a mixture. With the goal of understanding this complex organisation, the database continues to grow – here thousands of neurons blink into place in a 3D reconstruction, adding to the totalled length of 87+ metres of neurons mapped inside a brain the size of light bulb.

Written by John Ankers

Video from the MouseLight Project, Janelia Research Campus

Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA

Video copyright held by the original authors

Research published in Cell, September 2019

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[yeskitle]

Google, 50 Trilyon Piksellik Beyin Haritası Yayınladı

Google, 50 Trilyon Piksellik Beyin Haritası Yayınladı

Janelia araştırma kampüsü ve Google bilim adamları birlikte yaptıları çalışmalar ile şimdiye kadar ki en yüksek çözünürlüklü beyin haritasını çıkardı. Meyve sineğinin beyninin incelendiği araştırma 12 yıl sürerken, yaklaşık 40 milyon dolarlık bir maliyetle tamamlandı. Ortaya çıkan beyin haritasının 50 trilyon 3D Piksel‘den oluştuğu söylendi. Üstelik bu harita, meyve sineğinin beyninin “insan saç…

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[micdousmi]

VR simulator for mice helps researchers study Alzheimer's

VR simulator for mice helps researchers study Alzheimer’s

A group of scientists from Janelia Research Campus have built their lab mice some sort of an Oculus Rift of their own. Okay, so it's not a tiny VR headset for rodents — though that would have been amusing to see — but a simulator with walls that…

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[frontal-cortex]

And thus, it is Friday again.

Please share and like, really appreciate it !