Genetics influence cancer risk, but most cancers are not inherited.
Only a small portion come from inherited mutations. Warning signs include early cancer, repeated cancers across generations, multiple cancers in one person, or high‑risk ancestries such as Ashkenazi Jewish backgrounds.
Key genes include BRCA, Lynch‑syndrome genes, TP53, PTEN, CHEK2, ATM, PALB2, and RAD51 variants.
Lifestyle still drives the overwhelming majority of cancer cases, making diet, exercise, smoking habits, and weight essential factors. Genetic testing helps identify risk, but results require expert interpretation.
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