With Hera and Hestia suffering from “sleep sickness” (although I think Hestia has yet to be confirmed), and Poseidon stuck in a coma as well, it seems that with those who were injured by Kronos are being rendered ill. Since we don’t know the exact order the “Six Traitors” were injured in (save for Zeus how has never been injured by Kronos), and the varying degrees in which each was injured, this seems to be randomized, but growing. The effects of Kronos’ wounds cause immense pain and eventual coma. We don’t know when Poseidon fell. Hera fell at some point in the last ten years. Hestia took a turn around the time of Artemis’ and Apollo’s coronation ten years prior. We have yet to see how Demeter is being affected.
The main concern in Hades though. He has the most severe wounds of any of them, crisscrossing his body like a torn-apart and stitched-back-together doll. This “sleep sickness” that the others are going through seems to range, especially since at this point, we only know what Hera has been going through. And if that’s the extent that Hera went through after being bifurcated, imagine how much pain Hades will be going through, especially if it’s just getting started. Especially if this is leading up to Kronos’s rise.