#nanoparticle cell interactions

[raphavisses]

The long life of unicorns

The long life of unicorns

This article is a collaboration between a scientist and a philosopher. It tackles a very important issue : how do wrong beliefs sustain themselves in spite of lack of supporting evidence? Specifically, the article considers the belief in nanoparticles diffusing through biological membranes, i.e. one that is the topic of many computational studies as well as being regularly cited as a source of…

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[raphavisses]

Do nanoparticles cross membranes? Further thoughts on "Time of entry of nanoparticles in lipid membranes"

Do nanoparticles cross membranes? Further thoughts on “Time of entry of nanoparticles in lipid membranes”

This blog article has benefitted from discussions with philosopher Yasemin J Erden. The analysis presented here was originally part of a Perspective article co-written with her and focused on the question of how wrong beliefs (such as diffusion of nanoparticles through membranes) persist for a long time. We have decided to separate the detailed critique of Liu et al’s article (below) from the…

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[raphavisses]

Critical reading of "Predicting the Time of Entry of Nanoparticles in Lipid Membranes"

Critical reading of "Predicting the Time of Entry of Nanoparticles in Lipid Membranes" h/t @zk_nano #Nanoparticles #Nanomedicine

Thanks Zeljka for this reading advice: Predicting the Time of Entry of Nanoparticles in Lipid Membranes, by Changyang Liu et al.

Something to read carefully @raphavisses https://t.co/8vqLmcolzG

— Zeljka Krpetic (@zk_nano) September 20, 2019

https://platform.twitter.com/widgets.js

So I did. Not the details of the simulations (beyond my expertise) but the introduction and some key aspects of…

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[raphavisses]

Reply from Wolfgang Parak

Reply from Wolfgang Parak

Regular readers will remember a recent post where I documented the critical peer review of 20 influential (more than a 1000 citations) articles. I reviewed them initially in a Twitter thread and then also reproduced my comments on PubPeer.

Wolfgang Parak, corresponding author of one of these 20 papers (Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles), has kindly responded to my…

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[raphavisses]

20 critical reviews of influential articles about nanoparticles and cells

20 critical reviews of influential articles about nanoparticles and cells

I have commented on the 20 highly cited articles below. They all relate to nanoparticles and cells. They were published between 1998 and 2006 and have received more than 1,000 citations each, over 40,000 citations overall.

I have used Twitter to document my reviewing process.

In this thread, I will be looking back at highly cited (over 1000 citations) ‘historical’ (prior to 2008) bionano papers,…

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[raphavisses]

References for my talk at Gold 2018

References for my talk at Gold 2018

Slide 1:

Slide 2: Nanotech is bs Tweet.

Slide 3: Calling Bullshit.

Slide 4:  Dinosaur. (from here)

Slide 5: Electron microscopy of Hela cells after the ingestion of colloidal gold; C.G. Harford, A. Hamlin, and E. Parker; 1957

Slide 6: The entry and distribution of herpes virus and colloidal gold in Hela cells after contact in suspension; M. A. Epstein, K. Hummeler, and A. Berkaloff; 1963

Slide 7:

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