Discover Top Posts Tagged with #new pharma

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What is the size of the market for natural endogenous medicines that can be accessed safely via over the counter systems? What price would you pay for side-effect-free/reduced pharmacology? Products where the medical label did not include a dictionary list of probable unwanted side effects as long as the King James Bible, and as interpretable.

For example:

Analgesics — current market size ~50 billion, with estimates of 80 billion by 2035

Anti-Insomnia medicines — current market size 30 billion (including non drug products ~100+ billion)

Metabolic|Anti-Obesity medicines — e.g., GLP 1 - current market size 60-100+ billion (projected to reach 200 billion by 2035)

Assumption: with cannabis and biosynthetics, the current and future market value of the above examples would increase dramatically, due to singular origins (simple inputs: cannabis plant/compounds), and safety (addiction reduction/non existence, as well as the mild to minimal side effects due to the endogenous nature of the substances). Add all of the above examples together, plus those that have not been included or yet discovered, multiply by increased efficiency and safety factors, and you will begin to understand what the beginnings of such things could be, relative to where we are today. Imho. Oh, and also, the recreational products are also very valuable 😅 btw 🫳🏾 don't forget to add those as well.

Question: which company has access to both IP experience, patents, and capacity for in vitro and in vivo biosynthetic optimizations? And is also very good with plant handling operations? And is trading below book and sales/revenue value (forward and trailing)? 🤔 hmmm...

Things are going to get even more interesting thanks to global de/rescheduling. Biotech may have found it's first true cash crop 😅

*Not financial advice — only creative writing mixed with environmental scanning — Not financial advice. Side effects may include unexpected and/or underserved expectations of profit, free cash flow, growth, EBIT and EBITDA multiples. Earning expectations may be subject to financial accounting regularities according to jurisdiction and doctor's orders. Please see your doctor and financial advisor, as individuals and individual corporate results may vary.*

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New biomaterial regrows damaged cartilage in joints

Northwestern University scientists have developed a new bioactive material that successfully regenerated high-quality cartilage in the knee

Northwestern University scientists have developed a new bioactive material that successfully regenerated high-quality cartilage in the knee joints of a large-animal model.

Although it looks like a rubbery goo, the material is actually a complex network of molecular components, which work together to mimic cartilage's natural environment in the body.

In the new study, the researchers applied the material to damaged cartilage in the animals' knee joints. Within just six months, the researchers observed evidence of enhanced repair, including the growth of new cartilage containing the natural biopolymers (collagen II and proteoglycans), which enable pain-free mechanical resilience in joints.

#👀👏🏾❗...#New Pharma #material sciences

Newly discovered protein stops DNA damage

Researchers from Western University have discovered a protein that has the never-before-seen ability to stop DNA damage in its tracks. The f

Researchers from Western University have discovered a protein that has the never-before-seen ability to stop DNA damage in its tracks. The finding could provide the foundation for developing everything from vaccines against cancer, to crops that can withstand the increasingly harsh growing conditions brought on by climate change.

The researchers found the protein—called DdrC (for DNA Damage Repair Protein C)—in a fairly common bacterium called Deinococcus radiodurans (D. radiodurans), which has the decidedly uncommon ability to survive conditions that damage DNA—for example, 5,000 to 10,000 times the radiation that would kill a regular human cell. Lead researcher Robert Szabla says Deinococcus also excels in repairing DNA that has already been damaged.

"It's as if you had a player in the NFL who plays every game without a helmet or pads," says Szabla, a grad student in Western's Department of Biochemistry. "He'd end up with a concussion and multiple broken bones every single game, but then miraculously make a full recovery overnight in time for practice the next day." He and his colleagues discovered that DdrC is a key player in this repair process.

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Typically, says Szabla, proteins form complicated networks that enable them to carry out a function. DdrC appears to be something of an outlier, in that it performs its function all on its own, without the need for other proteins. The team was curious whether the protein might function as a "plug-in" for other DNA repair systems.

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#😳❗👏🏾...#DdrC #proteomics #Damage Repair Protein C #New Pharma #🐭