#nsaids

[shamebats]

A cautionary tale: I overused ibuprofen about 10 years ago, when my migraines went chronic. It wasn't so much the headaches but the prodrome, which is sudden overwhelming sleepiness, like narcolepsy ... when I had to drive anywhere, I'd need to pop ibuprofen to stay awake. A neurologist told me much later that since my brain was having an inflammatory reaction to the barometric change, that's why an anti-inflammatory NSAID would have helped. The bad news: I have stage 3a kidney disease. With no family history of kidney problems, the conclusion is I damaged my kidneys by NSAID overuse. There's a reason those warnings are (in very small print) on the label. See a neurologist; get a better abortive (like a triptan or a gepant) and a preventive med. We tend to think that OTC meds are safe ... but they all have risks.

[that-gay-jedi]

"Ibuprofen is a kind of angel" "Ibuprofen should grow on trees" "let's take Ibuprofen together" HAVE YOU HEATHENS HEARD OF CELECOXIB? SHE'S LIKE IF IBUPROFEN LOVED YOU BACK. Treat her properly and keep one of her besties (proton pump inhibitors) with her and you, too, can transcend the limitations* of your flesh long into the coming days.

* some of them, at least

(This is not medical advice, but this IS recognition of the divine.)

[chronicillnessresourcelibrary]

Arthritis Medications And The Sun Can Interact

Note: this resource is written by a NZ-based organization and is primarily aimed at people in Aotearoa NZ (where the ozone layer home makes the risk of sun damage much higher) but this is still crucial information for anyone on medications for arthritis and inflammatory conditions.

"The interaction of inflammatory arthritis (such as rheumatoid arthritis, psoriatic arthritis and other forms of spondyloarthritis), medications to control arthritis and sun sensitivity is not always clear, and the reactions between medications and sun vary; • NSAIDs, such as Naproxen and diclofenac, can make you more sun sensitive as can Sulfasalazine/ Salazopyrin. Hydroxychloroquine can increase light sensitivity and vision changes. • COX-2 inhibitors like Celecoxib can cause irritation, with a breakout in rashes... • There is an increased risk of non-melanoma skin cancers (NMSC) for people being treated with DMARDs such as methotrexate and some biologic therapies. These medications also increase the risk of NMSC recurrence. • Methotrexate can irritate the skin where sunburn has occurred previously... • Long-term corticosteroids thins the skin, making it more likely to burn, and more susceptible to wrinkling and thinning of the skin (skin atrophy)."

Arthritis, medication, and the sun

The interaction of arthritis, medications to control arthritis and sun sensitivity is not clear, and reactions between medications and the s

[hussyknee]

I'm so fucking mad.

Yesterday I took 50mg of Atomoxetine (Strattera) out of sheer frustration instead of my prescribed 30mg which was doing nothing.

And then...I was like "get up" and I would get up. "Go find the electricity bill" and went and found the electricity bill. "Sort through all the mail and organise it" and just. Fucking. Did it. No getting stuck for half an hour and spiralling in anxiety because my executive commands weren't going through.

I went to the hospital and begged those fuckers to increase my dosage and spent half an hour trying to convince them that this is clearly my ADHD symptoms being exacerbated by anxiety that's fucking me up. They refused, said "Oh, but anyone would find it difficult to function in your situation", and increased my Venlafaxine (Effexor) instead, although that fuckin plateaus any further than the dosage I already take. My primary doc knows this, but I have better luck catching Bigfoot than her at NHSL anymore so I keep having to tussle with the junior dipshits.

Granted I seem to have overshot a bit, because I spent a while vibrating into the fifth dimension. Felt like I'd had six cups of coffee and needed to do three things at once. Perhaps I should have attempted 40mg first. But 50mg very much did catapult me out of this neverending rut.

WEEKS OF BEING TRAPPED BY THE STATIC IN MY BRAIN LIKE A ROOMBA ON A RUG. I couldn't get out of bed, eat on time, shower, make my bed, do my laundry, go to bed. The simplest fucking tasks like pushing a boulder uphill with a stick. Sitting on the bed doomscrolling and tearing the soles of my feet into strips so bloody that it hurt to walk. I don't pick at my feet anymore! Didn't even realize I hadn't until the end of yesterday. This is the first time I've stopped in months. I stock up on band-aids and keep them next to my bed because I usually bleed in about three places within a day. And I pick the scabs off the still-healing wounds. All stopped by 20mg more of Strattera!!!

In other medication fuckery, I stopped the anti-inflammatory meds I was taking for my back because 1) the total cost of my meds was getting insane and 2) I haven't been in pain the last two months. I looked up whether there were side effects for long-term use of NSAIDs and found that using any of them with Venlafaxine increases the chance of gastrointestinal bleeding?? The way I've been having all this time?? Was my rheumatologist ever gonna tell me?? I'm just so used to flares, so fogged in my head and so relatively pain-free that I didn't especially note it. Turns out– the only reason I haven't been in pain is because I was taking the fucking anti-inflammatories. Imagine that! So I can either take Venlafaxine (which I cherish like a child regardless of the wrath-of-God withdrawal any time I miss a single dose) or I can take NSAIDs??

*googles anti-inflammatory meds other than NSAIDs*

Internet: "eat pineapple idk. have you tried tumeric?"

I hate my life.

[whump-me-plz]

As a tween, I had a scary moment with pain relievers. At the time, I was getting headaches daily, always after physical education class. Without many local providers to refer me to, my doctor at the time recommended pre-medicating with Tylenol before PE. And it worked. Until it didn't. One day, I pre-medicated after lunch as I always did. But after PE, I had another headache for the first time in a while. So I went up to the clinic and was given a second dose by a different person. When they went to document it, they found a dose had already been taken and panic ensued.

As it turns out, I had probably outgrown my current dose, so taking a second was likely not an overdose. However, I think ever since, there is a part of me that is scared of pain relievers. I'll take them. But almost never a full dose and only as a last resort.

That being said, I probably suffer more than necessary with pain. And I sometimes think of alternative delivery methods of pain relievers besides oral medications.

I'm not really going anywhere with this other than I probably need to get my butt out of bed and take a stupid NSAID

[macgyvermedical]

Hello. Can you write something about diclofenac and interactions? Where I live, Diclofenac is often used as a topical cream/gel to treat mild-to-moderate acute joint pain, like sprains, but it also comes in pill Form, and is apparently not supposed to be taken together with Ibuprofen, but I recently put some on an injured wrist, and would have liked to also take Ibuprofen but deliberatley didn't because interactions, and when I saw the doctor, and complained about the inconvenience/asked for advice on how to switch over, like by stopping the gel and taking Paracetamol overnight and then taking Ibuprofen the next day?..., and She said I didn't need to worry and it's only oral Diclofenac that has interaction with Ibuprofen, not topical, but how does that work/

——————————-

Sure!

So diclofenac is an NSAID, which is in the same category of drugs as ibuprofen, naproxen, aspirin, and meloxicam, ketorolac, and many others.

They all work by blocking a chemical called cyclooxygenase (COX).

Since they all work the same way, taking more than one at a time is like taking a lot of one at a time, and can lead to overdose.

With the diclofenac gel specifically, the COX blocking is limited right to the area of the pain, and doesn’t travel around the body at high enough amounts to cause an overdose, even if you’re taking another NSAID on top of it.

[lexrambeau]

Okay so I went to the urgent care and they told me I have bleeding in my stomach organ. So if you take NSAID’s for chronic pain, please be very CAREFUL. It’ll take about 3 weeks to fully repair my stomach lining

[mychemicalroadworkahead]

Bet you never thought you’d see medication head canons did ya?

Well now you are

I like to think that Tylenol is Acetaminophen’s dead name and that it’s a closeted trans medicine. The Acetaminophen works is by blocking pain receptors which is something that can be done by the hormone GABA. The way GABA works is that it binds to receptors in your brain so that other hormones don’t affect you as much. GABA is fairly common in anti anxiety meds and antipsychotics. So assume Acetaminophen is transitioning from a psychological medication to a pain medication, NSAID if we’re being specific. I think it based its name off Aspirin because it always wanted to be like Aspirin. So what if when it went to change its name the other NSAIDs went with it to show support. Aspirin stayed the same but Ibuprofen changed its name to Advil and Naproxen to Aleve. Now they’re all one big happy supportive family of NSAIDs.