Theorigin of Phyllanthus niruri is tropical America from there it spread as a weed to other tropic and sub tropics. It is a tropical annual herb shrub which grows as weed in moist humid waste land. Phyllanthus niruri is among more than 500 Phyllanthus species that are widely spread in temperate and tropical climates region Lizuka et al., 2007. It grows 30 40 cm in height, has small leaves and yellow flowers the stem has green capsule, and blooms with flowers with 5 white sepals and apical acute anther.38g of Mueller Hinton Agar was dissolved in 1000ml distilled water in a conical flask, the mouth of the conical flask was plugged with cotton woo wrapped in aluminium foil. This was sterilized in an autoclave at 121oC for 15mns. The media was removed and allowed to cool to 45oC, later poured into a sterilized plastic petri plates which were appropriately labeled. The present study revealed the antimicrobial activity and phytochemical screening of phyllanthus niruri. The antimicrobial activity of phyllanthus niruri shows great significant against pathogens which are responsible for common infections of skin, respiratory, urinary and gastrointestinal tracts. The phytochemical screening of oxalate, terpenoids, tannins, phenols, quinones, flavonoids, alkaloids, saponins and steroids were all found to be active within the plant. This bioactive phytochemicals present in P. niruri can be useful for further researches on the plant P. nururi since the phytochemicals have shown preclinical efficacies for treating human diseases’ which include hepatitis and HIV AIDS. This work has compiled the chemical constituents present and can be useful for further researches
A STUDY ON THE EFFICIENCY OF PHYLLANTHUS NIRURI IN AMELIORATING THE DRUG INDUCED OXIDATIVE STRESS IN Oreochromis mossambicus AND ITS COMPARISON WITH A HERBAL FORMULA LIV 52 | UTTAR PRADESH JOURNAL OF ZOOLOGY
In Oreochromis mossambicus, the hepatoprotective and antioxidant potential of Phyllanthus niruri and Liv.52 in alleviating paracetamol-induced hepatotoxicity is compared. When fish were exposed to various amounts of paracetamol, the TBA value increased while the total protein content decreased. The addition of Phyllanthus niruri and Liv.52 to the feed reduces reactive oxygen species (ROS), resulting in a lower TBA value, suggesting less lipid peroxidation. It's possible that the lower protein levels in these groups are due to increased protein utilisation for active metabolism and development. Fish fed Phyllanthus niruri had a lower TBA value than paracetamol-exposed animals, but fish fed commercially grown Liv.52 had an even lower TBA value than those fed Phyllanthus niruri, meaning that Liv.52, which is a mixture of many medicinal plants, has a greater protective effect. The t test is used to statistically analyse the results.
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Chanca piedra, or phyllanthus niruri, is a well known plant from the Amazon rainforest that has given naturopaths a powerful plant ally in supporting bladder, kidney, gallbladder, and liver health. Traditionally, chanca piedra is thought of as a health supplement that promotes the liver’s normal function by aiding the detoxification efforts that purge harmful substances. Chanca Piedra,…