AutoHotkey: Step 1
In my quest to find a qliner hotkeys replacement, I came across AutoHotkey bliss (I was looking for a replacement because qliner has a problem running on Windows 7 64-bit).
I love how powerful AutoHotkey seems to be and in literally 5 minutes I could look up and create this basic script for opening up 2 common folders I use everyday. The last line of the script is so that pressing only the right ALT button will open up Window's context menu that usually shows up when you right-click on something. Some keyboards have this key (AppsKey) but my Apple keyboard doesn't so this AutoHotkey script will automagically map the right alt key to this context menu key.
^1::Run C:\Users\elee\Downloads
^2::Run D:\
RAlt::AppsKey
edit: the Startup folder is so that you don't need to manually run each script every time you use your computer. Things in this special folder get run every time you start up Windows.