#small rna

[ihealthliving-blog]

Scientists discover suicide molecules that could kill any cancer cell

Scientists discover suicide molecules that could kill any cancer cell

In a recent study, researchers from Northwestern Medicine find that small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide.

This is the first study to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

The mechanism is RNA suicide molecules, which may be developed…

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[naddochuang]

My UNIX experience with sTarPicker

My primary attempt: INSTALLING sTarPicker

Check your Linux information (if it's 64- or 32-bit)

$ uname -a

Mine was x64. Download sTarpicker (Remember the folder you saved the file)

$ tar -xvf starpicker_64bit.tar

Look on the starpicker.pl file and look up for the module used in the Perl script (Indicated by :: --> double colon sign). It's better to install those Perl modules before proceed with the installation.

$ sudo cpan

It will pop out cpan[1]> , hence

cpan[1]> install Getopt::Long

Blablabla

cpan[2]> install Bio::SeqIO

Blablabla. It will ask some questions, just type whatever it is accordingly. If there's no error, so you're done with it. 

After few hours,

$ cd for64bitmachine/

$ tar -xvf ViennaRNA-1.8.4.tar.gz

$ cd ViennaRNA-1.8.4/

Try to root

$ sudo su

# ./configure

# make

# make install

# cd Utils

# cc -o b2ct btct.c

Hopefully there's no error pop out from the terminal. Go back and cd for64bitmachine

# cd for64bitmachine/

# ls -all

Check if the files form like this, -rwxrwxrwx@ something like that, if it's not

# chmod 777 * or # sudo chmod 777 *

Check again, so that to get something like this -rwxrwxrwx@.

Take a deep breath, try to use the example files provided in the folder as to test whether the installation took place correctly or otherwise. If there's no error, you should get an .output file with a result in it without any error line in the terminal. 

In conclusion, ihateunix huh!!!!

[rnomics]

Sneak Peak: #RNA-Sequencing Applications in #cancer Research: From fastq to differential gene expression, splicing and mutational analysis

Join us next Tuesday, April 12 at 10:00 am PST for a webinar focused on #RNA-Seq applications in breast #cancer research. The field of #cancer genomics is advancing quickly. News reports from the annual American Association of #cancer Research meeting are indicating that whole genome sequencing studies such as the 50 breast #cancer genomes (WashU) are providing more clues about the genes that may be http://bit.ly/z9JN1O #finchtalk