I obey God's will, my friend. My old friend. My eternal and everlasting friend...
--The Asphyx (1973)
Super-Slim was a miracle drug that became a global pandemic. It took less than a year.
The promises were unrealistic and no one would have believed them, if they hadn't delivered. Only three pills, taken over a three week period, and the fat just melted away. There were some minor side-effects: gastric distress, loose and greasy stool, and flatulence. The market was used to this, so these warnings were ignored. Going from a pot-belly to 2% body-fat in three months was too good to be true.
The government never approved its use, but the drive to be thin and beautiful was worth any risk. Even after someone had gotten a sample to a lab and proven it to be a bacteria (traced to a remote cave in the Tibetan plateau (and the ads had said it was an “ancient Tibetan secret”))—not a drug at all—those who desired its results could not be dissuaded. Those who sold it declared its safety loudly and showed how it could be easily purged with simple penicillin. The bloggers called it “The Modern Tapeworm” (and some even linked to on-line sites that promised discrete shipping).
Lab test after lab test did show it could be killed with current antibiotics. What was almost a panic subsided; except, after six months, the shakes started. People who had never taken the wonder pill were losing basic motor functions.
Users who had been “pooping out the pounds” introduced the bacteria to sewage systems and so it entered the water supply. However, antibiotics had entered the system as well and the bacteria developed a resistance. What was now in the wild was a stronger and more virulent descendant.
Children, once happy and hale, wasted to nothing and fell dead on playgrounds, the myelin coating protecting their nerves (the last source of lipids in their bodies) reduced to a slurry that quickly evacuated the body by any means necessary. Livestock were whittled down to red numbers on spreadsheets. Even ocean-going fish—tuna, salmon, and steel head trout—washed ashore, little more than scales and bones.
Bottled water was no safe haven, considering its source. Regular filters had no effect and soon "safe" water was only available through expensive (on a mass-scale) means.
Chinese pharmacies blamed Korean factories who, in turn, blamed Indian sources. The European Union blamed the Americans and the Americans blamed Brazil. World commerce ground to a halt as new restrictions appeared. Anything consumed by humans was suspect. Beef, pork, and chicken consumption halted (at least by humans), but humans themselves were being consumed by the ton.
It was a scramble to develop a vaccine. The bacteria had the uncanny ability to imitate red-blood cells. A simple vaccine would not work: it would either be ignored by the body or—and this was worse—the body would destroy its own blood-supply.
Bristlecone Labs had been working on the project since they had first heard the news. Their earlier success in finding a vaccine for Meningococcal disease (strain B, which imitates nerve cells), put them in a good position for finding a cure. Their genetics department had decoded the MenB bacteria and found the specific components that most typically caused infection. An order was placed with a Charles River supplier for two-hundred "Wistar" white rats.
The first tests were a disaster. The rats' droppings were loose and urine dark. The vaccine was destroying blood cells.
Bristlecone Labs ran through the two-hundred rats in a month. Charles River sent a new batch of Wistars.
With the new vaccine, these rats fared better, but not by much. The second formula left the blood alone, but destroyed the blood-producing organs and liver. Tweaks made to the vaccine had only minor effects.
By now, Bristlecone Labs' staff had reduced by fifteen people (due to illness). Charles River wasn't faring much better and having difficulty in keeping up with demand. With over three-hundred labs around the country racing for a cure, lab rats were becoming high-dollar item. Wistars were unavailable and Bristlecone Labs had to switch to Brown Norways. All of the research had to be started over.
Once Charles River ran out of Brown Norways, they suggested Nobles, which were mostly used in onocology research. Bristlecone refused the order and demanded a return of the Wistar rats (so they could continue with the previous research they had done). Charles River explained there were no Wistars left, but they could offer a discount on Copenhagens. They finally reached a deal when Charles River offered some Lacks rats (nick-named “Henriettas” by the breeders). These were usually used in cancer research, but were hardy animals that would not succumb to usual respiratory diseases that took out large, caged populations. Due to that, Charles River could provide the Lacks rats in greater quantities and at a lower price.
Desperate for test subjects, Bristlecone Labs accepted an order of five-hundred Lacks rats. The research would have to be restarted, again, but they had a greater working population and a promise of infinite supply.
The rats did not disappoint.
After only five weeks of testing, it looked like Bristlecone Labs had developed a working vaccine for the Super-Slim bacteria. Testing moved on to dogs and cats (despite the protests of PETA and the SPCA). Human trials started and (although they did eventually lose 5% of their subjects), Bristlecone Labs was ready to announce a working vaccine.
Money had already passed hands to the appropriate government agencies, so approval would not be far behind. As the world had been clamoring for a cure for nearly a year, any progress would be hailed as a miracle.
Confident in their success, the staff of Bristlecone Labs had taken the vaccine themselves. Executives made a public show of it: rolling up their sleeves for the TV cameras and grinning.
Ben Bluth was a low-ranking lab technician and had been tasked with disposing of the left-over rats from the testing phase. These rats had all been subjected to either the vaccine or the bacteria. After loading the cages into the gas-chamber, he turned on the supply and left to have a quiet dinner of instant noodles.
When he returned, the rats were not dead. Thinking there was a fault in the gas supply line, Ben Bluth checked the line a second and third time and tried again. This time, his belly already full of instant ramen, Mr. Bluth had time to watch the process.
The Lacks rats did express some discomfort and he could hear their tiny coughs through the gas-chamber's door; but, even after an hour of exposure, the rats did not expire.
Fearing the repercussions of not disposing of the rats as he had been tasked, Mr. Bluth panicked and decided to take the rats, one-by-one, from the cages and break their necks. The first rat did produce a loud snap; and, when placed back in the cage, it was unable to keep its head upright. But, the rat still moved about the cage and squeaked (although coarsely).
Believing himself to be hallucinating due to illness, Mr. Bluth left the lab and retired to his quarters on campus. As there was no time-restriction for disposing of the rats, he decided to wait until the next morning to complete the task.
Mr. Bluth's roommate, a Don Willard, came to bed some time after 2 AM. The staff had been celebrating their success with an impromptu party.
Mr. Bluth woke to find Mr. Willard dead the following morning. Mr. Willard had vomited a copious amount of a substance that looked a great deal like coffee grounds (and most likely unrelated to alcohol consumption) and his pale, yellow body was unresponsive to Mr. Bluth's repeated attempts to revive him.
Furthermore, attempts to contact emergency services were unsuccessful. Not knowing what to do, Mr. Bluth returned to the lab to finish the prior night's duties. To avoid the direct and uncomfortably bright morning sun, Mr. Bluth took an alternate path from the lab to his quarters. He found two corpses on the north side of the administrative building, both surrounded by the coffee-grounds like vomit. Knowing what partially-digest blood looked like, Mr. Bluth came to the conclusion that the vaccine was still a failure.
The lab was empty, but the rats (still in the gas-chamber) were alive and demanding something to eat. The rat with a broken neck continued to move about the cage.
Mr. Bluth, with no written procedure for action if the gas-chamber failed, took individual rats by the tail and swung them against a wall. These rats squeaked loudly and bled from the mouth, but still moved about once returned to the cage.
Thinking about the three bodies he had encountered that morning, Mr. Bluth thought perhaps his own response had been delayed. In either case—failed vaccine or disease—would be an unpleasant death. Mr. Bluth wheeled out the rats and entered a gas-chamber himself, having pre-set the controls. After an hour of feeling groggy, he let himself out of the gas-chamber and returned to his quarters. He still suspected that the gas-chamber was faulty, but the rats he had stuck against the wall raised doubts.
Mr. Willard's body was still in its bed when Mr. Bluth entered their shared quarters. Unable to find any pills in the room suitable for his purpose, Mr. Bluth resorted to a warm bath and razor blade.
Three hours later, Mr. Bluth awoke in a cold and sticky bath. He showered and bandaged his arms, although he suspected they would not heal without platelets. After preparing and consuming another cup of instant ramen, Mr. Bluth returned to the lab to check on the rats he had been tasked with destroying.
As the rats were still not dead, Mr. Bluth decided to release them. They did not run to the door, nor scurry under furniture—as he suspected they would—but clustered around his feet. In disgust, Mr. Bluth returned once more to his quarters.
The rats followed him and he allowed it. They swarmed the bed where Mr. Willard's body was and quickly nibbled it to the bone.
Mr. Bluth watched the process with scientific detachment, then did an inventory of his supply of instant ramen.
He decided he would need more.