The thing about Brigid Tenenbaum and Grace Holloway that I find especially interesting is the ways knowledge fits into both their arcs.
Tenenbaum being at the center of the ADAM project means that she knows all the gory details of how gatherers/protectors are made and what the process does to a person’s body. At the same time though, the horror of what she’s done by allowing her research into the hands of people like Ryan, Fontaine, and Lamb (as well as her own self-loathing for being the source of all that suffering) don’t fully dawn on her until it’s too late to do much besides mitigate the damage already done. And then in Bioshock 2, when she returns to Rapture hoping to develop a cure for ADAM sickness and rescue the little sisters from Lamb, there’s a whole decade of new research she has only limited knowledge of. She needs the thinker’s computational abilities to aid her research because as intelligent as she is, solving this problem (of her own invention) wouldn’t be possible for her to do alone before she died. She knows so much and yet due to the nature of the society she lived in and the miracle she discovered, there will always be something new she doesn’t know.
And then there’s Grace. She had no part to play in creating the Little Sisters or Big Daddies, so she doesn’t fully know why their existence is such a tragedy, but if her misguided hatred of Delta for Eleanor becoming a little sister is anything to go off of, she knows something. She knows on some level how wrong it is, but because of her faith in Lamb she’s still willing to accept that the little sisters wandering around rapture are children of the family. That even if he turns them human again, subject delta is stealing these girls from their rightful family, and she remains ignorant of the truth until it quite literally comes looking for her. If she lives, she survives with the knowledge that Lamb was wrong about this, so what else might she be wrong about? And her last words in canon are her saying she needs answers from Lamb about what the truth really is. Grace doesn’t know the exact science of how ADAM works, but somewhere deep in her heart she knows more of the awful truth than Lamb wants her to know, and that knowledge is what drives a wedge between her and the family
And I just think that’s a really cool parallel. Tenenbaum understands the evil she’s created better than anyone but even she has to make peace with how there will always be so much more she doesn’t know; Grace doesn’t understand the reality of what she’s been enabling all these years and has to come to terms with the fact that she knew all along.








