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@a-civil-ian
man sometimes friendship really is just "I saw this and knew it would give you psychic damage. please respond with agony" and then they do. and it's great
are you guys hearing about this dude working to developing a vaccine for cats that he's hoping would like. theoretically double their lifespans?
turns out i wasn't making that up, his name is Dr. Toru Miyazaki! he also wrote a book called "The Day Cats Live To Be Thirty", so cats are kind of his thing.
apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.
As they age, almost all cats develop kidney disease, from which they eventually die. Just as in humans, kidney disease i
Dr. Toru Miyazaki’s AIM injection for cat kidney disease enters trials in 2025, aiming for a 2027 release. Greycoat Research supports the sc
whoa wait i actually read the articles and it's so much cooler than just that!!
dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!
although his research was focused on cats, it's already being used to develop drugs for humans too!
on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.
furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.
annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D
man just think, not only could our kitties start living longer, healthier lives, but just maybe dialysis will become as rare and obsolete as the iron lung is for people. what a badass Dr. Toru is!
"But I don't want to turn people into dinosaurs. I wanna cure kittie kidneys!"
Update: So they have done clinical trials and have submitted it for approval as of april 2026. They are expecting it to be available late 2026/early 2027
The AIM protein drug for feline chronic kidney disease has been submitted for approval in Japan (April 2026). We break down clinical trial d
As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%
New 2026 study: AIM protein boosts cat kidney disease survival from 20% to 80%. Discover how this scientific breakthrough is changing the fu
Our cat Scout is in the early stages of kidney disease. This might be available in time to save her!
[Getting so angry it makes my brain disease worse] people sre supposed to be nice..
Yet another new study debunked the basis for the anti-trans sports bans. It was never about sports but for creating legal avenues for exclusion and abjection. This is one of the largest analyses ever conducted, involving 52 studies and 6,485 trans people. Read the study here.
post so nice had to reblog it twice and force it down everyone's throats
At minimum about 4.5 thousand people liked this without reblogging it.
We gotta fix that.
Progress.
Onwards!
Common Words & Phrases from AAVE
Gullah & Early AAVE
Gumbo – From Bantu kingombo (okra), brought by enslaved Africans and became the name of the Creole stew thickened with okra.
Goober – From Kikongo nguba, the Bantu word for peanut that entered American English via enslaved Africans.
Yam – From West African languages (e.g., Wolof nyami, "to eat"), brought over during the slave trade and adopted into Southern cuisine.
Banjo – From a Bantu root (mbanza), the instrument was crafted by enslaved Africans based on West African string instruments.
Bogus – Likely from Hausa boko-boko (deceitful, fraudulent), entering American English through African American speech in the 19th century.
Juke (box/joint) – From Gullah juke (rowdy, disorderly), derived from Wolof dzug (to live wickedly), later attached to roadside bars.
Tote (to carry) – From West African languages (e.g., Kikongo tota, "to pick up"), recorded in Gullah before spreading to mainstream English.
Dig (to understand) – From Wolof degg (to understand), popularized by jazz musicians in the 1930s after entering English through AAVE.
Jazz – Possibly from West African or Creole slang for energy/sex, first documented in AAVE in Chicago around 1912.
Okay (OK) – Though its origin is debated, strong evidence traces it to West African languages (e.g., Wolof waw kay) via enslaved Gullah speakers.
Hip/Hep – From Wolof hipi (to open one's eyes, to be aware), entering jazz slang in the early 1900s before going mainstream.
Hepcat – A compound of "hep" + "cat" (jazz slang for a person), literally meaning "one who has his eyes open" in West African-influenced jazz culture.
Jazz, Blues & 1940s–60s Era
Cool (as in fashionable/calm) – Originated in jazz circles, likely from saxophonist Lester Young, and entered mainstream via West African aesthetic concepts of composure.
Cat – A jazz-era term for a skilled musician or cool person, derived from West African-influenced jive talk.
Crib – Jazz slang for a house or apartment, popularized in the 1940s before becoming mainstream in the 1990s.
Hokum – AAVE slang for nonsense or BS, used in blues and jazz before being adopted more widely.
Diss – Short for "disrespect," coined in AAVE and popularized through hip-hop in the 1980s and 1990s.
Bad (meaning good) – From AAVE, where inversion of meaning creates emphasis (something so "bad" it's actually good), used since early jazz era.
Jive – AAVE slang for deceptive talk or a style of jazz dancing, used by Cab Calloway in his 1930s Hepster Dictionary.
1970s–90s (Hip-Hop & Pre-Internet Era)
Homeboy/Homegirl – AAVE for a close friend from one's neighborhood, popularized in hip-hop and later shortened to "homes" in casual speech.
Dope (meaning great) – Shifted from "stupid" in standard English to "excellent" in AAVE during the 1980s hip-hop era.
Props – Short for "proper respects" in AAVE, used in hip-hop to acknowledge skill or achievement before entering mainstream slang.
Word (as in "I agree") – AAVE interjection ("Word!" or "Word is bond") meaning "I'm telling the truth," derived from Nation of Islam teachings.
Phat (meaning cool/great) – AAVE acronym believed to stand for "Pretty Hot And Tempting," though likely an invented backronym; popularized in 90s hip-hop.
The Bomb – AAVE phrase for something excellent or top-quality, widely used in hip-hop lyrics before mainstream adoption.
Def – AAVE slang for "excellent," popularized by Run-DMC's "King of Rock" and 80s hip-hop culture.
Fresh – AAVE for stylish or excellent, used in early hip-hop and 80s pop culture before spreading globally.
Wack – AAVE for "bad, inferior, uncool," popularized in hip-hop and later mainstream youth speech as the opposite of "cool."
Hella – AAVE intensifier meaning "very" or "a lot of," originating in Oakland/Bay Area AAVE in the 1970s-80s.
Cap / No Cap – AAVE meaning "lie" and "no lie," popularized by Bay Area rap in the 2010s, derived from "capping" (exaggerating).
1990s–2000s (Internet Adoption & Ballroom Culture)
Slay – From AAVE and Black ballroom culture (Paris is Burning, 1990), meaning to do something extremely well, now mainstream via social media.
Spill the Tea – From AAVE (originally "spill the T," with "T" meaning truth), popularized by drag culture and Black queer communities.
Shade (as in insult) – From Black ballroom culture (documented in Paris is Burning), meaning a subtle insult, now used broadly in pop culture.
Reading (as in insulting) – From ballroom culture ("reading" someone), meaning to publicly insult with wit, immortalized in Paris is Burning.
Kiki – AAVE from ballroom culture meaning a casual gathering for gossip or chatting, later mainstreamed through pop music (e.g., Kesha).
Fierce – AAVE and ballroom term meaning exceptionally good or intense, applied to fashion, performance, or attitude.
Woke – From AAVE meaning socially and politically aware, first used in 1940s Black activism before resurging with Black Lives Matter.
Shook – AAVE meaning startled or upset, used in 1990s New York hip-hop (e.g., Mobb Deep) before mainstream adoption in the 2010s.
On Fleek – AAVE phrase meaning perfectly executed, coined in a 2014 Vine by Peaches Monroee, one of the last pre-AI viral AAVE innovations.
Finna – From AAVE contraction of "fixing to" (preparing to), documented in Southern AAVE for decades before wider use and dictionary recognition.
Chile – A phonetic spelling of "child" in Southern AAVE, used as a term of endearment or exclamation since at least the 1970s (The Wiz, 1978).
2010s–Present (Social Media & Gen Z Slang Pipeline)
Lit – AAVE meaning exciting or excellent (originally "intoxicated" or "on fire"), popularized in hip-hop before becoming a Gen Z staple.
Bae – AAVE term of endearment meaning "before anyone else" or just a shortened form of "babe/baby," mainstreamed in the 2010s.
Ratchet – AAVE originally meaning a rowdy, aggressive woman (from "wretched"), later used to describe anything wild or out of control.
Turnt – AAVE meaning excited or intoxicated, from "turned up" in hip-hop lyrics, mainstreamed in early 2010s party slang.
Clap Back – AAVE for a sharp, witty comeback or retaliation, popularized in hip-hop (e.g., Ja Rule's 2003 song "Clap Back") before internet slang.
Bussin' – AAVE meaning delicious or excellent, applied to food or anything great, popularized on TikTok in the 2020s.
Sus – AAVE shortening of "suspicious" or "shady," used for decades before Among Us made it a global meme in 2020.
Snatched – AAVE originally describing flawless hair/makeup or a tight waist, now used to praise anything perfectly executed.
Periodt – AAVE emphatic form of "period" (meaning "end of discussion"), with a hard "t" for emphasis, popularized on Black Twitter before global use.
Bonus: My personal favorite AAVE term that I see used online religiously is receipts! AAVE meaning the proof shown to back up an accustation
Anyway dni if you still support Cain, he hit his brother over the head with a fucking rock and it killed him instantly (source). I truly do not know how he still has fans. It astounds me how people can call themselves good people and still be completely fine platforming blatantly Abelist assholes like him. Smh
Non cooking spray stick
Non spray stick cooking
Non cooking stick spray
yeah okay ill reblog that
Happy Neil Day! Please enjoy the very rare alternate Neil images!
aroace nonbinary people you are everything to me. shout out to the bitches who just said "nah i'm not doing any of that"
The psychiatrist diagnosed me with divine madness
any other diagnoses you'd like to share?
Autism
I have a crush. Absolutely terrible experience
How it feels to ask a friend to do an activity with you even though you Know both of you will enjoy it and they've never been mean about doing it with you before and you'll both have a great time
take and take and take (click for quality!)
ko-fi ☕ patreon 🥪 merch ❇️
i CANNOT express how much more lovable my friends are to me at their most annoying. i'd rather hear the same story 3 times than not at all. i'd rather read a 22 message text rant about something totally inconsequential than not hear from you all day. i'd rather you tag me in the stupidest post i've ever seen than not know that it made you think of a conversation we had a month ago. BE ANNOYING AT ME. I LOVE YOU
As an adult you must cultivate the skill of “Gross! Oh, well. Not my business.”
Applies to everything from BDSM parties to your sister’s godawful interior design choices to weird bachelor pad meals eaten over a sink.
Gross! Oh, well. Not my business.