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Tanjore Brahadeeswara temple, Tamil Nadu, India

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How can you just leave someone’s life? How is it so easy for you? What do you do with all the memories of us laughing and talking at 4am, and habits of texting ‘Good morning’ and ‘Goodnight.’ How can you just leave that? Did you never care at all?

I want to believe you miss me, but deep down I know you don’t. ( @humanhealing )

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Cannes, France (by Gerhard Bopple)

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Genetically Altered Skin Saves A Boy Dying Of A Rare Disease

A child who was on the verge of death from a rare inherited disease has been treated with genetically engineered skin cells that replaced most of the skin on his body.

The treatment represents a notable success for the field of gene therapy, which has suffered many setbacks. And it’s potentially good news for children suffering from a painful and often deadly skin condition called epidermolysis bullosa.

In this disease, children are born with a flawed gene that prevents prevents the outer layer of the skin, the epidermis, from binding to the inner layer. This can cause excruciating blisters to form all over these children’s bodies.

In the case in Europe, a 7-year old boy ended up in the hospital back in 2015 after 60 percent of his epidermis had sloughed off. Tobias Rothoeft, a surgeon at a burn unit at Ruhr University in Bochum, Germany, says he and his colleagues tried everything — including a skin transplant from the boy’s father — to no avail.

“After nearly two months we were absolutely sure there was nothing we could do for this kid and that he would die,” Rothoeft said in a telephone news conference hosted by Nature, which published the study online Wednesday.

Rothoeft and his colleagues took one last look around the medical literature and learned of researchers in Italy who were experimenting with a new treatment for this disease. Michele De Luca and colleagues at the University of Modena and Reggio Emilia, were genetically engineering skin cells to repair the inborn flaw.

De Luca used a virus to insert a healthy gene into cells taken from the boy’s skin. Some of those cells, stem cells, multiply indefinitely. So De Luca was able to grow entire sheets of engineered epidermis, which were shipped to the hospital in Germany.

Photo: CMR Unimore/Nature