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@bonitafish
Mesothelioma of the Kidney
Thanks to television commercials, most people in the US are probably aware of the main cause of mesothelioma - up to 85% is caused in the lungs from asbestos exposure, especially in people who worked in mines or construction prior to the 1980s.
However, mesothelioma can form in any mesothelium, which is a tough membrane of simple squamous epithelium that makes up the peritoneum, mesentery, pleura, and pericardium.
When it comes to renal (kidney) cancers, it turns out that renal cell carninoma can mimic the appearance of mesothelioma more frequently than renal mesothelium becomes malignant.
Genito-Urinary Surgery and Venereal Diseases. Edward Martin and Benjamin Thomas, 1918.
I think some people are just inexplicably bonded. Drawn by forces beyond their own comprehension, they have no choice but to gravitate toward one another. Destined by fate to keep crossing paths until they finally get it right.
L.B. Simmons (via wordsnquotes)
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Stargazing
Current Screening Methods Miss Worrisome Number of Persons with Mild Cognitive Impairment “False-negatives” mean persons at greater risk for Alzheimer’s disease may not get timely care
Mild cognitive impairment (MCI) is a slight but noticeable and measurable decline in cognitive abilities, such as remembering names or a list of items. While changes may not be severe enough to disrupt daily life, a clinical diagnosis of MCI indicates an increased risk of eventually developing Alzheimer’s disease or another type of dementia.
In a paper published in the current Journal of Alzheimer’s Disease, researchers at University of California San Diego School of Medicine and Veterans Affairs San Diego Healthcare System say existing screening tools for MCI result in a false-negative error rate of more than 7 percent. These persons are misclassified as not having MCI based on standard screening instruments, but actually do have MCI when more extensive testing is conducted.
“There are consequences to misdiagnosis,” said first author Emily C. Edmonds, PhD, a postdoctoral fellow of neuropsychology in the Department of Psychiatry at UC San Diego School of Medicine. “At the individual level, people incorrectly identified as cognitively normal might not receive appropriate medical advice or treatment. This could include preventive measures, such as diet or lifestyle changes to maintain cognitive function, or a referral to other health care providers.”
Beyond that, Edmonds said diagnostic errors can also negatively impact research studies of MCI and early Alzheimer’s disease. “If research participants are misclassified when they enroll in a study, this can weaken the study’s results, which makes it even more difficult to find and develop effective treatments or therapies.”
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