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Weight loss and diabetes prevention: brown fat cooling research

Cold for Weight Loss and Diabetes Prevention Washington Post Interviews Leading Brown Fat Researchers The energy burning furnace that keeps our body warm when exposed to cold, brown fat or brown adipose tissue, has been increasingly studied for its role in metabolism for weight loss and diabetes prevention. Mouse studies show active brown fat has…

Weight loss and diabetes prevention: brown fat cooling research was originally published on Brown Fat for Health

#beige fat #brown fat #brown fat cooling vest #cooling vest for weight loss #diabetes prevention #good fat #iceman study

Weight Loss Vest: Top 5 Facts

Top 5 Facts About Weight Loss Vest Research

What studies say about cooling vests and brown fat weight loss

COMMENTARY

A brown fat weight loss vest must use mild cold

A weight loss vest cooling vest using ice packs or any cooling packs cold enough to trigger shivering are not going to properly activate brown fat to increase your metabolism and burn more calories. Brown adipose tissue uses a process called “non-shivering thermogenesis.” Non-shivering thermogenesis is the body’s natural response to mild cold. Very cold temperatures cause shivering which is a short-term and entirely different reaction by the body where rapid muscle contractions generate heat. The point where your body’s response shifts from non-shivering to shivering thermogenesis varies by individual, but is around 58 degrees Fahrenheit. Cooling vests for brown fat weight loss should not use ice cold cooling packs of thirty degrees Fahrenheit. Ice cold cooling vests and packs also create a danger of skin damage and burns from freezing. Activation of brown fat using non-shivering thermogenesis is best with special phase change material (PCM) cooling packs that can be designed to have a melting point at or around 60 degrees Fahrenheit.

A weight loss vest should cover more body surface area

Using a cooling vest for brown adipose tissue stimulation is simply a more practical solution for what you can accomplish either by being outside in mild cold temperatures or being in a mild cold room kept at or around 60 degrees Fahrenheit. Naturally the more surface area that a cooling vest covers on the body the more closely it simulates being in a cold environment. Check the size of the cooling packs that are held by any weight loss cooling vest product. Calculate the total area the cooling packs will cover to compare how effective the cooling vest may be for brown fat activation.

Cool fat burner: use a cold room?

Brown fat cooling packs should be designed to make full body contact

How does a cooling vest work? Cooling packs against your body act like a heat sink. There is a thermal exchange between your body and the cooling pack. While the cooling pack is colder than your body it draws heat away from your body and cools your body. So the more direct body contact made by your cooling pack, the better the performance. Ideally, flexible cooling packs with a flat surface are used that conform to the body and are held in place by a well designed vest using compression to hold the packs firmly to the body.

A longer lasting weight loss vest is better

Studies of brown fat cooling have all used mild cold exposure but for varying lengths of time and temperature. Cooling vests that have been used for scientific research to date have been chilled water circulation vests that require connection by tubes to a chiller. Time periods for the water circulation vests have been no more than a couple of hours. So the longer a cooling pack stays cold in a cooling vest for brown fat, the longer your cold exposure and logically the effectiveness. A cooling vest designed to allow easy removal of warm packs and replacement with cold spares can allow extended mild cold exposure.

A weight loss vest for brown fat should be designed for comfort and exercise

Of all considerations, comfort and freedom of movement for exercise and long wear time is key to gaining the benefits of brown fat cooling. Encouraging regular use and convenience is essential. While no studies have explored the combination of exercise and cooling to date, having an athletic cooling vest design to allow exercise in the cold should provide the most effective health benefit. The key is to hold the cooling packs tight to your body and keeping them from bouncing and moving during exercise.

While these are the five key factors in purchasing a cooling product for brown fat health benefits, keep in mind others are important such as: style, fit, quality, warranty, and value for your money. Do your own research about what makes a real product that is a true cool fat burner and study the truth about freezing your fat off.

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Weight Loss Vest: Top 5 Facts was originally published on Brown Fat for Health

#beige fat #brown fat #brown fat cooling vest #brown fat diabetes #brown fat obesity #cooling vest for weight loss #turn temperature down for weight loss

Brown Fat Cooling Vest to Treat Childhood Obesity: Door Opens to Research

Research Opens Door to Study of Brown Fat Cooling Vest in Children

Childhood Obesity Crisis

As you can see in the above graph, Childhood obesity is perhaps the greatest health crisis facing the United States and the world. Recently published research which included the use of a brown fat cooling vest to activate brown adipose tissue, showed that less expensive, non-invasive readings of skin and core temperature may be used to study the effect mild cold exposure has on brown fat activity which could lead to the study of brown fat cooling for childhood obesity.1)1 jQuery("#footnote_plugin_tooltip_3152_1").tooltip({ tip: "#footnote_plugin_tooltip_text_3152_1", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [10, 10] }); To date measurement has involved radiation exposure using an MRI or PET scan, which would rule out studies involving children even though safe mild cold exposure using a cooling vest is a potentially safe, non-pharmaceutical treatment for childhood obesity and related metabolic disorders such as diabetes.

Brown adipose tissue (brown fat or BAT) has always played an important role in maintaining a steady state body temperature in mammals and has been newly discovered to have a role in people. Because BAT studies have shown the potential path towards new treatments for obesity and related metabolic disease like diabetes, new ways to research human BAT activity that are less expensive and invasive can lead to breakthroughs for our health. The most exciting opportunity is to open the door to studying the impact of mild cold exposure using a brown fat cooling vest for children that is safe, effective, and simple to use at an affordable cost.

Study Method Included Brown Fat Cooling Vest for Mild Cold

A trial was conducted that included 18 men who were divided into two groups. Using known PET and MRI methods of measurement, but adding measurements of skin temperature and body core temperature, the groups were 10 who already had pronounced BAT activity and 8 who had little to no BAT activity. Exposing these volunteers to mild cold using a combination of room temperature controls, liquid cooling vests and blankets, allowed the scientist to determine if skin and core temperature measurements could be used instead of PET and MRI methods.

Results of the study provided further proof that mild cold exposure triggers a response in brown fat in humans to maintain core body temperature just like any mammal. There was a strong correlation between the volume of brown fat in person and response to cold. Most significant was the finding that “…the significant correlation between the cold induced change in core and supraclavicular [skin temperature at the collar bone] temperature suggest those two measures as a potential [measure] of BAT activity.”

These safer, non-invasive, non-radiation, easier to perform and less expensive measurements of brown fat can open the door to the study of the effectiveness of treatments for obesity include the safe use of mild cooling with a brown fat cooling vest for children. This would provide an option in the near term to help fight the childhood obesity epidemic.

2) jQuery("#footnote_plugin_tooltip_3152_2").tooltip({ tip: "#footnote_plugin_tooltip_text_3152_2", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [10, 10] }); Chondronikola M, Volpi E, Børsheim E, Chao T, Porter C, Annamalai P, Yfanti C, Labbe SM, Hurren NM, Malagaris I, Cesani F and Sidossis LS (2016) Brown Adipose Tissue Is Linked to a Distinct Thermoregulatory Response to Mild Cold in People. Front. Physiol. 7:129. doi: 10.3389/fphys.2016.00129

References [ + ]

1. ↑ 1

Brown Fat Cooling Vest to Treat Childhood Obesity: Door Opens to Research was originally published on Brown Fat for Health

#brown fat #brown fat cooling vest #childhood obesity #cooling vest for weight loss

Brown Fat Cooling and Exercise

Brown Fat Cooling During Your Workout: A Hot Fitness Trend? Combining exercise with brown fat cooling may accelerate metabolism A leading researcher who authored a book on diet and lifestyle changes to manage diabetes has encouraged using a cold exercise room for brown fat cooling. Dr. George King, the head of research at the Joslin…

Brown Fat Cooling and Exercise was originally published on Brown Fat for Health

#brown fat cooling vest #cooling vest for weight loss

Brown Fat Diabetes Cooling Research: Major Positive Glucose Uptake Boost

Brown Fat Diabetes Cooling Study of Cold Acclimation Shows Profound Increase in Insulin Sensitivity in Only 10 Days

Before and After Glucose Uptake Results Cold Acclimation of BAT. Copyright Nature

A recent study of brown fat diabetes evaluating the promise of cooling as a therapy for people with type 2 diabetes published on nature.com added to mounting evidence of major benefits. People with type 2 diabetes participating in the study of brown fat cooling showed better improvement in their insulin sensitivity than seen in the currently most recommended therapy of long term exercise for diabetes. “Insulin sensitivity was markedly increased after cold acclimation as indicated by on average a 43% increase in the glucose infusion rate….”

After just 10 days of cold acclimation people in the study with type 2 diabetes showed very significant positive impact on both whole-body and skeletal muscle sensitivity to insulin. As a result glucose uptake is markedly improved leading the researchers to conclude that brown fat cooling is a valid new way to improve the metabolic health of people with diabetes.

The method of cold acclimation to study the area of brown fat diabetes cooling therapy was remarkably simple and short. Eight overweight males were included in the study which originally was intended to include eleven to obtain valid results. During the study of the initial eight subjects the results on insulin sensitivity from cold acclimation of brown adipose tissue (brown fat) were so significant that the study was shortened with the approval of an external research monitoring board. During the ten day cold acclimation test, the study subjects were in a room kept at 14-15 degrees centigrade with exposure times increased starting with 2 hours on day 1, 4 hours on day 2, and 6 hours on days 3-10. Patients in the study used their normal medications for type 2 diabetes, ate standardized meals at the same time and were told not to exercise.

Exciting opportunities for brown fat diabetes cooling therapies are opened up by this key study, with a cooling vest for brown fat weight loss and diabetes treatment being one that is convenient. The combination of both brown fat cooling and exercise for diabetes treatment is another exciting concept: one that Dr. George King, head of research at Joslin Diabetes Center is already exploring at the Harvard Medical School institution’s headquarters where a “Joslin Coolout” workout in a cool room has started.

Brown Fat Diabetes Cooling Research: Major Positive Glucose Uptake Boost was originally published on Brown Fat for Health

#brown fat #brown fat diabetes #cooling vest for weight loss #turn temperature down for weight loss

Benefits of Cold: Brown Fat Weight Loss

Brown Fat Weight Loss Health Benefits of Being Cold: The ATLANTIC Jan/Feb 2015 Issue The Atlantic’s “FAT Nation” Cover Many new research studies are examining the benefits of stimulating brown fat, the common name for brown adipose tissue, using the natural method of cold exposure. Ice vest or cooling vest products have started to appear…

Benefits of Cold: Brown Fat Weight Loss was originally published on Brown Fat for Health

#beige fat #brown fat #brown fat diabetes #cooling vest for weight loss #turn temperature down for weight loss

Brown Fat Diabetes Fighting Organ ?

Brown Fat Diabetes Research Published

Researchers find that brown fat is an anti-diabetes organ

Diabetes may be treated by stimulating brown fat

Not all fat is created equal, and that is good news for millions fighting diabetes. In a study of the metabolic role of brown fat diabetes researchers at the University of Texas Medical Branch at Galveston showed that people with more brown fat are able to maintain control over their blood sugar and increase their resting metabolic rate. 1)

Chondronikola M. Brown Adipose Tissue Improves Glucose Metabolism and Whole Body Insulin Sensitivity in Humans. Scientific Session of the American Diabetes Association, San Francisco, June 2014.

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How did they do it? The study, led by Dr. Labros Sidossis, included adult male subjects who were divided into two groups: one group had brown fat present at the start of the study and the other did not. All subjects wore a cooling vest for several hours at a mild cold temperature that would stimulate brown fat and not cause a shivering response.

The results showed that active brown fat plays an important role in metabolism of glucose. People in the study who had stores of brown fat that were activated by the cooling vest were better able to metabolize glucose and had increased insulin sensitivity. The abstract of the study states:

“These results demonstrate a physiologically significant role of BAT in whole-body energy expenditure, glucose homeostasis, and insulin sensitivity in humans and support the notion that BAT may function as an anti-diabetic tissue in humans.”

Researchers found that mild cold exposure increased the base metabolic rate of the brown fat positive group by 15%. Very significant reductions in blood glucose were seen in the individuals with cold stimulated brown fat.

While some studies have lowered thermostats in a room to create mild cold conditions, this is the third study to use a liquid circulating cooling vest or garment connected by tubing to a chiller. 2)

Blondin, Increased brown adipose tissue oxidative capacity in cold-acclimated humans, J Clin Endocrinol Metab doi:10.1210/jc.2013-3901 1)(Cypess, Cold but not sympathomimetics activates human brown adipose tissue in vivo, PNAS June 19, 2012, vol. 109, no. 25.

jQuery("#footnote_plugin_tooltip_2").tooltip({ tip: "#footnote_plugin_tooltip_text_2", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [10, 10] }); While effective, using a brown fat cooling vest that keeps you connected to a chiller by tubes requires the person to remain still and is not practical for real world use. The water cooled vests are very expensive devices used by surgeons to remain cool during long procedures. Cooling is acknowledged as the best know way to stimulate brown fat, but researchers are mainly focused on finding a drug as a treatment for obesity and diabetes. Cooling vests with phase change cooling packs to activate brown adipose tissue may provide the best solution.

References

↑ Chondronikola M. Brown Adipose Tissue Improves Glucose Metabolism and Whole Body Insulin Sensitivity in Humans. Scientific Session of the American Diabetes Association, San Francisco, June 2014.

↑ Blondin, Increased brown adipose tissue oxidative capacity in cold-acclimated humans, J Clin Endocrinol Metab doi:10.1210/jc.2013-3901 1)(Cypess, Cold but not sympathomimetics activates human brown adipose tissue in vivo, PNAS June 19, 2012, vol. 109, no. 25.

Brown Fat Diabetes Fighting Organ ? was originally published on Brown Fat for Health

That Doughnut is Killing your Brown Fat

Killing your Brown Fat New Brown Fat Research links Obesity Diet to Brown Adipose Tissue Damage Brown fat and its related beneficial beige fat have only recently been shown to be important to adult humans. Now researchers have found that feeding an obesity diet chow to mice that is high in sugar and fat damages brown…

That Doughnut is Killing your Brown Fat was originally published on Brown Fat - Weight Loss and Health

Brown Fat Cold Exposure

Brown Fat Cold Exposure : ICEMAN Study Presented Room temperatures proven to influence brown fat growth or loss Today an exciting new study of the effect of room temperatures on brown fat cold exposure was presented in Chicago at a meeting of the International Society of Endocrinology. “Our research points to a simple and practical brown…

Brown Fat Cold Exposure was originally published on Brown Fat - Weight Loss and Health

#beige fat #brown fat #cooling vest for weight loss #turn temperature down for weight loss

Sleep Disorders and Weight Gain

Brown Fat Activity, Sleep Disorders and Weight Gain Brown adipose tissue at the intersection of sleep and temperature regulation Lack of sleep is “a public health epidemic” according to the Centers for Disease Control and Prevention in the United States. Sleep disorders and weight gain go hand-in-hand and play a role in our obesity epidemic…

Sleep Disorders and Weight Gain was originally published on Brown Fat - Weight Loss and Health

Role Brown Fat in Humans Workshop

Report on: Exploring the Role Brown Fat in Humans February 25 – 26, 2014 Hosted by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) “A workshop focused on elucidating the roles of recently described brown and beige fat or brite fat in people. Speakers will describe state-of-the-art technology for monitoring human brown adipose…

Role Brown Fat in Humans Workshop was originally published on Brown Fat - Weight Loss and Health

Beige Fat and Brown Fat Explained

Research shows Beige Fat works like Brown Fat Mild cold and exercise stimulate creation of “beige fat” in white adipose tissue Our whole focus on fat, weight loss and obesity has been rooted in looking at white fat which is the “bad fat” that we find so hard to eliminate. White fat or white adipose…

Beige Fat and Brown Fat Explained was originally published on Brown Fat - Weight Loss and Health

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