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@capsulehealth
Sick sinus syndrome (SSS)
Sick sinus syndrome (SSS)
Sick sinus syndrome (SSS) is a group of abnormal heart rhythms (arrhythmias) presumably caused by a malfunction of the sinus node (primary pacemaker). Tachycardia-bradycardia syndrome Variant of SSS in which the arrhythmia alternates between slow and fast heart rates Associated with: Ischemic heart disease Heart valve disease Aetiology Scarring/degeneration/damage to SA…
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Premenstrual syndrome (PMS)
Premenstrual syndrome (PMS) refers to physical and emotional symptoms that occur in the 1-2 weeks before a woman’s period. Linked to the luteal phase Clinical features More than 200 different symptoms have been associated with PMS Common emotional and non-specific symptoms: Stress, anxiety, difficulty with sleep, headache, malaise, mood swings, increased emotional sensitivity, and changes in…
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Iliopsoas abscess
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Herniated intervertebral disk
Herniation of ucleus pulposus due to damaged annulus fibrosus compressing the nerves or spinal cord causing pain and spinal cord dysfunction. Etiology Intervertebral disc:Intervertebral disc is composed of annulus fibrous—the annulus fibrous, dense collagenous ring encircling the nucleus pulposus. Disc herniation occurs when part or all the nucleus pulposus protrudes through the annulus…
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Diabetic Foot Syndrome
The presence of several characteristic diabetic foot pathologies such as infection, diabetic foot ulcer and neuropathic osteoarthropathy is called diabetic foot syndrome. Pathophysiology Diabetic neuropathy (peripheral & autonomic)Mechanical disruptionVascular insufficiency (Diabetic microangiopathy)Impaired tissue healing Presentation Pain, as well as reduced sensations of…
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Reactive arthritis (ReA)
Inflammatory arthritis that manifests several days to weeks after a gastrointestinal/genitourinary infection. Reactive Arthritis falls within the subclass of seronegative spondyloarthropathies that affect the axial skeleton. Other members of that group: Ankylosing spondylitisPsoriatic arthritis History: Hans Conrad Julius Reiter was a German Nazi physician and war criminal who conducted…
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Wilms' tumor
Wilms’ tumor
Wilms’ tumor (nephroblastoma) is an embryonal renal cancer. Also known as nephroblastoma (as cancer arises from metanephric blastema cells of kidney) History: Timeline of key clinical advances that established the modern clinical management of children with Wilms tumour: 1) The National Wilms Tumour Study group (NWTS), which was supplanted by the Children’s Oncology Group (COG) in 2002, and…
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Acute respiratory distress syndrome (ARDS)
Acute respiratory distress syndrome (ARDS)
Acute disorder characterized by bilateral lung infiltrates and severe progressive hypoxemia in the absence of any evidence of cardiogenic pulmonary edema within 7 days of an inciting event. Etiology ARDS represents a stereotypic response to various etiologies. Sepsis (M/C cause)Inhalation of harmful substances: High concentrations of smoke or chemical fumes, aspiration of vomit or…
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Pulmonary edema
Abnormal accumulation of extravascular fluid in the lung parenchyma. Etiology Cardiogenic pulmonary edema: Volume-overload pulmonary edema due to elevation in hydrostatic pressure of pulmonary capillaries. Left ventricular systolic and diastolic function (acute myocarditis including other etiologies of non-ischemic cardiomyopathy, acute myocardial infarction)Valvular function (aortic/mitral…
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Axial spondyloarthritis (axSpA)
Spondyloarthritis (SpA) encompasses a group of rheumatic disorders that share clinical, genetic and radiographic features and includes psoriatic arthritis, reactive arthritis and arthritis of inflammatory bowel disease (IBD). These disorders affect 2–3% of the population and are twice as common as rheumatoid arthritis. The spectrum of spondyloarthritis (SpA) and overlap (cross-sectional and…
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Colorectal Cancer
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Gastric cancer
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Testicular cancer
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Superior Vena Cava Syndrome (SVCS)
Superior Vena Cava Syndrome (SVCS)
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Rhabdomyolysis (RML)
Rhabdomyolysis is the destruction of skeletal muscle with resultant release of intracellular enzymatic content into the bloodstream that leads to systemic complications Muscle necrosis + release of intracellular muscle constituents into circulation Clinical definitions: In 2002, the American College of Cardiology (ACC), American Heart Association (AHA), and National Heart, Lung, and Blood…
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Nasopharyngeal angiofibroma (NA)
(Juvenile) Nasopharyngeal angiofibroma (JNA) is a rare, highly vascular, histologically benign but locally invasive tumor, affecting predominantly male adolescents. The earliest known documentation of nasopharyngeal angiofibroma (NA) dates to Hippocrates in the fifth century B.C. Commonly referred to as juvenile nasopharyngeal angiofibroma (JNA), it is also known as juvenile angiofibroma (JAF),…
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Nasopharyngeal carcinoma (NPC)
Nasopharyngeal carcinoma (NPC), previously known as lymphoepithelioma, is a malignancy arising from the epithelium of the nasopharynx. Epidemiology Approximately one third of nasopharyngeal carcinomas of the undifferentiated type are diagnosed in adolescents or young adults. Although rare, NPC accounts for one third of childhood nasopharyngeal neoplasms (data from…
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