A Short Guide to Testosterone for Trans and Non-Binary Individuals
[Trigger Warning: Mentions genitalia and menstruation]
The goal of testosterone treatment is to aid in the masculinisation of AFAB people by increasing their serum testosterone to that of a cisgender male’s range. A lower dosage of testosterone can also be administered to non-binary individuals who wish to have a more androgynous appearance, though a lower dose may simply result in changes occurring more slowly.
It is available in the form of:
Injections: Sustain and Nebido.
Topical gel: Testogel and Testim.
Capsules (rare): Restandol Testocaps.
Patches: Androderm and Testoderm.
When taking testosterone it is important to be aware of the changes that will occur as well as potential side effects.
Changes to expect when taking testosterone:
Increased oiliness of the skin (potential for acne to develop): Changes seen in 1-6 months | Little change expected after 1-2 years | Reverts if testosterone stopped |
Clitoral enlargement: Changes seen in 1-6 months | Little change expected after 1-2 years | Permanent |
Periods stop: Changes seen in 2-6 months | Continual with testosterone usage | Reverts if testosterone stopped |
Vaginal atrophy and dryness (not all will experience this): Changes seen in 3-6 months | Little change expected after 1-2 years | Reverts if testosterone stopped |
Body fat redistribution: Changes seen in 3-6 months | Little change expected after 2-5 years | Reverts if testosterone stopped |
Facial and body hair growth: Changes seen in 3-6 months | Little change expected after 3-5+ years | Permanent |
Deeper voice: Changes seen in 3-12 months | Little change expected after 1-2 years | Permanent |
Increased muscle mass and strength: Changes seen in 3-12 months | Little change expected after 2-5 years | Reverts if testosterone stopped |
Male-pattern baldness onset (may be minimal or not occur): Changes seen in 12+ months | Variable changes | Reverts if testosterone stopped |
Potential side effects of taking testosterone include:
Acne.
Headaches.
Dizziness.
Hypertension.
Increased blood pressure.
Lipid derangements.
Polycythemia.
Reasons a testosterone prescription could be withheld/deemed inadvisable for the patient:
Pregnancy.
Heart failure.
Obstructive sleep apnea.
Unstable coronary artery disease.
Untreated polycythemia.
Please keep in mind that changes occur at different rates for different people.











