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List of Juniper Publishers PubMed Indexed Articles.

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Design of Nano Polymer Orthoses

Authored by Gilberto Pavani

This work has the opinion of the authors about the conception, design and manufacturing processes of nano polymer orthoses as an interface between the organic and inorganic realities through the symbiogenic approach mediated by assistive technologies that aim to fulfill and amplify the functionalities of the human body. The development of orthoses requires serious study of the human singularities, needing an approach that integrates different areas of knowledge such as physiology, design and material engineering in order to satisfy the needs of people with reduced functional capabilities. The objective of this work is to broaden the discussion about independence and the safe practice of social activities that involve work, leisure and sports, using orthoses developed with nano polymer, aiming to offer more comfort to the user, for being lighter, more resistant and more durable than the existing products, as well as being recyclable, helping with the preservation of the environment.  

To Read More...PHP in  Global Journal of Nanomedicine in Juniper Publishers

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Potential of Porous Silicon Doped With Gold Nanoparticles in Detection of Biogenic Amine. Porous Silicon Used in the Detection of Biogenic Amines

Authored by Francisco Severiano Carrillo

Due to its properties porous silicon is a material with high potential to be applied in bio-delivery carriers and biosensors. To enhancement the capacity of porous silicon as biosensor, gold nanoparticles are introduced in its structure. One of the most used methods to obtain porous silicon/Au nanoparticles is metal salt-assisted chemical etching. The high surface of porous silicon matrix and the Au nanoparticles allow the increment of the sensitivity of the biosensor. This structure can be use as platform to got a biogenic amine optic biosensors. This kind of sensors (optic) are based on the changes of the signals related to the reactions between biogenic amines and the recognized element used (diamine oxidase).

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Nanotechnology and Mesenchymal Stem Cells for Regenerative Medicine

Authored by Ana I Flores

Nanotechnology has emerged as an area with great potential for the treatment of several human diseases. The use of nanobiomaterials, drug delivery systems, gene therapies, diagnostic and surgical robotic tools, nanobiomedical devices, amongst others, is called nanomedicine or bio-nanotechnology in healthcare. It has been shown that stem cells have an important reparative potential for restoring the function of injured tissues and organs. Nanotechnology and stem cell research are two interesting fields that are gradually becoming a newly merged field of modern research. This novel field, stem cell nanotechnology, has generated high interest in human healthcare because it could result in significant contributions in regenerative medicine and tissue engineering. Mesenchymal stem/stromal cells or mesenchymal stromal cells (MSCs) are a special type of stem cell with some interesting properties, such as easy isolation, high rate of proliferation in culture and their differentiation capacity into several cell lines. Moreover, it has been shown that MSCs contribute to tissue repair due to their tropism for injury sites. It has been proposed that MSCs can be useful as cellular vehicles for medications. Human MSCs have been isolated from different tissues such as bone marrow, adipose tissue, cord blood, Wharton’s jelly, dental pulp and placenta. The new field of MSCs/nanobiomaterials could give challenging advances in tissue regeneration in the next decade.

To Read More...PHP in Global Journal of Nanomedicine in Juniper Publishers

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Synthesis and Characterization of Pure and Co doped Zinc oxide

Authored by Jyotsna Chauhan

Present work is a study on synthesis and Characterization of pure ZnO and Co doped nanoparticles by using chemical co-precipitation method. We have doped pure ZnO with Co by 3% mole concentration. Structural and optical properties of these nanoparticles are analyzed by using XRD, UV-Visible spectroscopy. We found the crystallite size of range 20 nm to 30 nm.

To Read More....PHP in  Global Journal of Nanomedicine in Juniper Publishers

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Biodegradable Topical Nanogels in the Treatment of Skin and Superficial Tumors

Authored by Arun K Iyer

Nanogels are nano-sized three-dimensional polymer networks engineered by physical or chemical cross-linking of individual polymer chains loaded with drugs and nucleotides that swells in a good solvent.

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Nano Chemotherapy: An Emergent Anti-Cancer Modality

Authored by Alain L Fymat

The notion that even relatively indiscriminate cytotoxic agents discovered largely by accident would cure cancer continues to captivate oncology. Thus, with a three-drug cocktail called BVP (bleomycin, vinblastine, cisplatin abbreviated P for platinum), metastatic testes cancer can be cured, and a high-dose cocktail of seven drugs can cure Burkitt’s lymphoma. From there, an avalanche of such drugs have poured in: taxol, Adriamycin, etoposide, bleomycin (an antibiotic), and an alphabet soup of other combinations (ABVD, BEP, C-POMP, ChlaVIP, CHOP, ACT). Yet, despite these successes and the escalation of drugs and doses, the efficacy of the drug regimen remains minimal. The pattern repeats itself regularly for many forms of cancer. Fortunately, through the ability of nano particles and the nano devices that deliver these drugs more efficiently and more judiciously at tumor sites, nano chemotherapy (NCT) is evolving as an emergent, viable anti-cancer modality that builds upon and supplements conventional chemotherapy. This article introduces NCT and discusses the several nano particles and the nano devices delivering them that have been found useful. The clinical advantages of this novel strategy are outlined as well as ways of overcoming multi-drug resistance. However, like for any anti-cancer modality, toxic effects may be lurking in the background and are briefly considered.

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Green Synthesis of Silver Nanoparticles using Hybanthusenneaspermus Plant Extract against Nosocomial Pathogens with Nanofinished Antimicrobial Cotton Fabric

Authored by Sankareswaran M

Nosocomial infection is defined as an infection which develops 48 hours after hospital admission or within 48 hours after being discharged that was not incubating at the time of admission at hospital. Nosocomial infections (NI) are frequent complications of hospitalizations. The issue has been recognized for more than a century as a critical problem affecting the quality of health care and a principal source of adverse outcomes. Medicinal plants are plants containing inherent active ingredients used to cure disease or relieve pain. The main objective of this research is to impart antimicrobial finish to cotton fabrics and to produce medical apparel from the finished fabrics. Thus the present study provided different products of medical importance, which could be used in different medical and healthcare applications. This work we investigated cost effective and environment friendly antibacterial properties of cotton fibers loaded with silver nanoparticles (AgNPs) synthesized from natural plant extracts as a reducing and capping agent.

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Controlling Amphiphilic Functional Block Copolymers’ Self-Assembly: From Structure to Size

Authored by Fei Liu

Nanostructure of self-assembled particles, such as micelles and polymersomes play an important role in drug delivery, especially in tumor therapy. Particles with various structures and proper sizes (20~500 nm) are regarded as perfect candidates for controlled drug delivery due to controllable size that benefits the extended permeation and retention (EPR) and high payload that increases drug delivery efficiency. In this review, we summarized recent representative studies in controlling the size and structure of Amphiphilic block copolymers self-assembled particles with pH- and temperature responsiveness.

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Prospects and Challenges of Graphene-Based Nanomaterials in Nanomedicine

Authored by Arghya Narayan Banerjee 

Graphene is considered to be the ‘wonder material’ because of many unique and fascinating properties, such as high mechanical strength (200 times stronger than steel. 

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Prospects and Challenges of Graphene-Based Nanomaterials in Nanomedicine

Authored by Arghya Narayan Banerjee 

Graphene is considered to be the ‘wonder material’ because of many unique and fascinating properties, such as high mechanical strength (200 times stronger than steel.

To Read More...PHP in Global Journal of Nanomedicine in JuniperPublishers