Knowing that Yuuta uses "san" for Isaburou and "sama" for Sano makes me think that perhaps he is not as close to Sano-kun as he is to Ebisu, but why might that be? We know that he looked after Ebisu when he was younger, so in theory he must have known Sano as a child š§
There is also this part when they travel to the Meiji era and Ren meets the Ogata twins:
I think the gods reincarnate like in Noragami or something similar.
Leaving theories aside, haha... as a YuutaxEbisu shipper, I like to think that Kurahashi is more formal and respectful towards Sano (in his Susanoo version) because he doesn't entirely like the fact that Sano is worshipped by Ebisu and is somewhat angry about it.