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FAQs about Getting (Dapoxetine) Priligy Online - Get All the Answers
Learn everything you need to know about obtaining (Dapoxetine) Priligy online with our all-inclusive FAQs. Learn about the application process, eligibility criteria, and potential benefits. Find answers to common queries, confirming a smooth and informed experience. Allow yourself with the knowledge to make confident decisions in securing (Dapoxetine) Priligy through online channels.
Dapoxetine: a pharmacological therapy for the treatment of premature ejaculation
Premature ejaculation (PE) is one of the most common male sexual dysfunctions, characterized by reduced intravaginal ejaculatory latency time (IELT) and self-perceived lack of control over ejaculation. PE can place a substantial burden on the sexual satisfaction of the couple and negatively impact their quality of life. Dapoxetine is a short-acting selective serotonin reuptake inhibitor and the first pharmacotherapy approved for the treatment of men with PE. The pharmacokinetic profile of dapoxetine makes it particularly well-suited for the on-demand treatment of PE. Dapoxetine has been investigated in five randomized, placebo-controlled Phase III trials involving 6081 men with PE. Dapoxetine (30 and 60 mg) significantly increased mean IELT across the trials (p ≤ 0.001 both doses vs placebo) up to 24 weeks. Increases in IELT with dapoxetine were observed in men with baseline IELTs ranging from less than 0.5 to 2.0 min, and were accompanied by improvements in patient-reported outcomes (control, satisfaction, distress and interpersonal difficulty) for both the man and his partner. The approval of dapoxetine offers new hope to men with PE.
Australian Public Assessment Report for Dapoxetine
https://www.tga.gov.au/sites/default/files/auspar-priligy.pdf
Dapoxetine is a short-acting potent serotonin reuptake inhibitor (SSRI). Serotonin is thought to play a role in ejaculatory reflex mediation and is believed to act centrally and peripherally to inhibit ejaculation, perhaps via the serotonin (5HT)1a receptor. In the original application to the TGA, the proposed therapeutic indication for dapoxetine was for the treatment of premature ejaculation in male subjects aged 18-64 years who have the following:
i) persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes,
ii) marked personal distress or interpersonal difficulty as a consequence of premature ejaculation, and
iii) poor control over ejaculation.
DAPOXETINE FOR THE TREATMENT OF PREMATURE EJACULATION
Dapoxetine is a short acting SSRI licensed for the treatment of premature ejaculation in men aged 18-64 years who meet the following criteria: o An intravaginal ejaculatory latency time (IELT) of less than two minutes; and o Persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes; and o Marked personal distress or interpersonal difficulty as a consequence of PE; and o Poor control over ejaculation; and o A history of premature ejaculation in the majority of intercourse attempts over the prior 6 months. Dapoxetine dose is 30-60mg orally as required but maximum once every 24 hours.
DAPOXETINE tablets
Dapoxetine is a short-acting SSRI. A pooled analysis of 4 randomised controlled trials in men with PE evaluated the effect of ‘on-demand’ dapoxetine on IELT compared with placebo. This analysis demonstrated a statistically significant increase in IELT from baseline with 30mg and 60mg of dapoxetine compared with placebo (from 0.9 minutes in all groups to 1.9, 3.1 and 3.6 minutes respectively for placebo, dapoxetine 30mg and dapoxetine 60mg, for comparison with placebo).
It has been suggested that the minimum clinically important change in IELT appears to be about 1 minute; however, the minimum clinically important change in IELT has not been defined in clinical practice. There are no head-to-head trials comparing ‘ondemand’ dapoxetine with daily use of SSRIs.
What PRILIGY is used for
PRILIGY is a treatment for premature ejaculation (PE) in men 18 to 64 years old who have all of the following: ejaculation in less than 2 minutes following vaginal penetration, on most occasions, with little stimulation and before the man wishes to; and marked personal distress and interpersonal difficulty as a result of premature ejaculation (premature ejaculation troubles the man and his partner); and poor control over ejaculation. PRILIGY contains the active ingredient dapoxetine and is a type of drug called a selective serotonin reuptake inhibitor (SSRI) and it is also known as a urological medicine. PRILIGY increases your time to ejaculation and can improve your control over ejaculation and reduce your distress over how fast you ejaculate. This may improve your satisfaction with sexual intercourse. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason. This medicine is available only with a doctor's prescription.